Analysis Of Model For End-stage Liver Disease Score And Prognosis On Patients With Decompensated Liver Cirrhosis

BackgroundImprovement of the course and outcome of the patient's disease is a primary objective of doctors.Thus,assessment of the patient's prognosis is an important part of the evaluation,which will have a significant influence on the choice of therapy.The Child and Turcotte classification(1964) and the Pugh's modification(1973) (Child-Turcotte-Pugh[CTP]score) were originally devised for the assessment of the severity of liver disease in predicting the outcome of patients with cirrhosis.The Model for End-Stage Liver Disease(MELD) is a new scoring system for severity of liver disease.It is very popular and has been widely used as a prognostic tool and also used for allocation in liver transplantation(LT) waiting lists and other fields.But the research of MELD is still not enough in China.ObjectiveTo evaluate the short term survival prognosis of patient s with decompensated liver cirrhosis by means of model for end-stage liver disease(MELD).Methods83 patients with decompensated liver cirrhosis were analyzed with MELD scoring system.The death rate were observed within 3 months. Results18 patients died within 3 months and the mortality of 83 patients with decompensated liver cirrosis was 21.69%.The average MELD scores of all the patients was 14.04±9.08.The MELD(25.33±10.11) levels were higher than those survivors (P<0.01).The mortality of whose with MELD<10,10≤MELD<20,20≤MELD<30, MELD≥30 was 3.3%,12.1%,57.1%and 83.3%respectively.The differences were all highly significants(χ~2=31.5,P<0.01).The mortality of those MELD≥18 and MELD <18 was 61.9%and 8.1%,the difference was highly significant(χ~2=28.6,P<0.01).ConclusionThe MELD scoring system can accurately predict short prognosis for the patients with decompensated liver cirrhosis.