Effect Of Treating Hyperglycemia Of Type 2 Diabetes With Insulin Pump

Objective:To investigate and analyze the effect and insulin dosage of continuous subcutaneous insulin infusion(CSII)in type 2 diabetes.Methods:46 hospitalized patients with type 2 diabetes,who had poorly controlled blood glucose,were treated by insulin pump for 8 days, without oral hypoglycemic agents.The treatment days when blood glucose was well controlled and the insulin dosage at that time were observed.The related factors for the therapeutic effects were analyzed.Results:When blood glucose were well controlled,the mean time was 5.4±1.8 days,the basal insulin was 0.23±0.07(u/kg,day),the bolus before breakfast was 0.12±0.05(u/kg).The bolus before dinner was 0.14±0.06(u/kg),the bolus before supper was 0.14±0.06(u/kg). The dosage of insulin was decreased after blood glucose were well controlled.The frequency of hypoglycemia was 0.04±0.21(times/per patient),the frequency of biochemical hypoglycemia was 0.07±0.25 (times/per patient)and reaction of hypoglycemia was 0.96±1.18 (times/per patient).Conclusion:The hyperglycemia of type 2 diabetes can be corrected by intensive insulin pump within 5-6 days.Multiple regression shows that fasting blood glucose and age are the factors that affect the time for blood glucose to be targeted.Duration of diabetes,fasting and postprandial blood glucose levels before treatment affect the required insulin dosage.