Study On Chemical Constituents From Delphinium Campylocentrum Maxim.

Thirteen compounds were isolated from the whole herb extract from Delphinium campylocentrum Maxim, and eleven of them were elucidated clearly based on the modem spectroscopic technologies including 1D- and 2D- NMR, MS, HRMS, CD, IR, etc. In such process, one novel hetidane-type diterpene skeleton, campylopin (1), and two new norditerpenoid alkaloids, campylocine (2) and campylotine (3), along with eight known alkaloids: delbrunine (4), talassimine (5), talassamine (6), talassimidine (7), deltatsine (8), delbonine (9), dehydrodeltatsine (10), and delbrunine monoacetate (11) were firstly discovered in this plant. The discovery of compound 1 implies a new biosynthetic pathway from the atisane or hetidane-type diterpene to the hetidine-type diterpenoid alkaloid.