Study On Clinical Application Of Percutaneous Mitral Balloon Valvuloplasty

Objective:This study reports the clinical data of 215 patients who underwent percutaneous balloon mitrail valvuloplasty(PBMV)in order to study on indications, complications,mid and long-term results of percutaneous balloon mitral valvuloplasty in patients with mitral stenosis.Methods:From January 1993 to december 2006,215 patients were registry,including 44 male(20.47%)and 171 female(79.53%),with age of 18-68(mean age of 40.70±11.62).There were mitral stenosis with atrial fibrillation,with left atrial appendage organized thrombus,with pregnancy,with mitral stenosis Left atrium diameter complicating pulmonary stenosis and atrial septal defect and Lumtembacher's syndrome.5-10 year follows-up(mean 5.1±2.4 year)were in 83 patients.The data including pre-PBMV,post-PBMV 2 day and 5-10 years follow-up clinical and echocardiography results were studied retrospectively by SPSS software. Results:After PBMV,mitral valve area(MVA)increased from 1.02±0.26cm~2 before PBMV to 1.93±0.57cm~2(p＜0.01).There were 93.49%patients who had at least one class improvement in cardiac function NYHA just after PBMV.At 5-10 years follow-up in 83 patients,survival rate was 98.8%,81.93%patients were still in classⅠorⅡ,MVA decreased to 1.69±0.27cm~2 gradually,restenosis rate was 32.53%.Atrial fibrillation, cardiac function and Wilkins' score before PBMV were correlated factors with restenosis after PBMV,P＜0.05.Conclusion:PBMV can achieve excellent and sustained mid and long-term results,especially sinus rhythm,Wilkins' score≤8,without poor cardiac function may have the best long-term results.