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The Relative Study Between Cervical Atherosclerotic Plaque With Its Inflammatory Factor And The Type Of Syndrome In Cerecral Ischemic Stroke(CIS)

Posted on:2008-06-05Degree:MasterType:Thesis
Country:ChinaCandidate:Y ZhouFull Text:PDF
GTID:2144360215965221Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Objective:To review the patients of CIS, analyzing the relationship between CIS and the incidence of cervical atherosclerotic plaque, further discussing the relative study between cervical atherosclerotic plaque with its inflammatory factor and the type of syndrome in CIS,studying the the type of syndrome in different stage of CIS,comparing the relativity of the different type of syndrome and the blood fat between the patient with CIS,observing the blood stream parameter of carotid artery, the character of the plaque and the sclerotic degree among different stages by BUS,further discussing the important effect of the character and instability of cervical atherosclerotic plaque which causes the CIS.Methods:To collect the cases diagnosed as CIS were in hospital in the first attached hospital of Guangzhou TCM university(mainly in the first internal section) from June in 2004-2006 year,making the statistic and analyzing of parameter in both sides of common carotid artery and the intercarotid artery with the plaque and the inflammatory factor, especially the relativity between the thinness of IMT and the character of the plaque the type of syndrome in cerecral ischemic stroke(CIS).Results: 1.The age of males hit by stroke is with no significance compared to females'. There are 187 (72.76%) cases with cervical atherosclerotic plaque in the whole 257 cases.And there are 62 cases (33.16%) with single plaque while others are 127 cases (66.67%) with multiply plaque;2.The team of CRP and I1-6 which are positive with plaque is with significant difference compared to the negative (P<0.05), and the level of CRP in the syndrome of hyperhepatic yang and wind-fire upper disturb are higher than others,while the level of I1-6 in the qi-asthenia and blood stasis are higher than others.It tips that the level of inflammatory factor is with significant difference in different kinds of syndrome (P<0.05).3.The strong facula is with much proportion in every type,and the type of hyperhepatic yang and wind-fire upper disturb, qi-asthenia and blood stasis are with significant difference compared to others;4. The majority of type in acute stage group is "wind phlegm and stasis-blood obstructs the meridians",while in restoration and sequela stage group is "qi-asthenia and blood stasis" (P<0.05);5. The means of Tc and TG in the type "phlegmopyrexia causing fu syndrome and wind-phlegm upper disturb" is with significant difference compared, to other types of CIS (P<0.05), while others are with no difference;6.In different age stage there are with significant difference compared to normal value in different parameters of separate carotid artery.Conclusions:CIS is relative to the incidence of cervical atherosclerotic plaque,and most of them are multiply plaque (66.67%);The level of inflammation factor rising unnormally is with highly relativity of cervical atherosclerotic plaque; The level of CRP in the syndrome of hyperhepatic yang and wind-fire upper disturb are higher than others,while the level of I1-6 in the qi-asthenia and blood stasis are higher than others.It tips that the level of inflammatory factor is with significant difference in different kinds of syndrome (P<0.05); The strong facula is with much proportion in every type,and the type of hyperhepatic yang and wind-fire upper disturb, qi-asthenia and blood stasis are with significant difference compared to others.It tips that the character of cervical atherosclerotic plaque is with significant difference in different kind of syndrome in CIS.
Keywords/Search Tags:cervical atherosclerotic plaque, CIS, inflammatory factor
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