| The diabete's foot (Diabetic Foot is abbreviated as DF) is a complication with the diabetic disease. DF is the chronic progressing disease that causes damage to nerve, bloodvessel, skin, tendon, even skeleton and necrosis to foot of the patients eventually. It is important factor that makes the sufferers disable. KangmaiⅢCapsule comes from tutor LiLing Gen Professor, who have been using it to treat peripheral vascular disease such as DF etc. for 20 years and summarized the clinical findings and gets a favorable curative achievement. In this project, We selecte 40~75 year-old's patients as the samples in accord with the DF diagnostic standard and use KangmaiⅢCapsule to treat DF, then we study this medicine's mechanism of the therapy about treating DF, analyse and appraise KangmaiⅢclinical curative effect synthetically. The method as follows: We selected 40 patients treated by KangmaiⅢCapsule as therapeutic group and other 20 patients treated by Tongsaimai tablet as control group. And we observed the changes of the patients' symptom, physical sign, blood-fat, hemodynamic, ET, TXB2, 6-K-PGF1αin plasma before and after the treatment. Results showed that KangmaiⅢCapsule could obviously lowers patient DF plasma ET, TXB2 and raise NO, 6-K-PGF1α, and was superior to control group in this aspect. The Consult is that after treating with KangmaiⅢCapsule, there had notable improvements in ET, NO, TXB2, 6-K-PGF1αin patient's plasma. So we can draw a conelusion : KangmaiⅢplays a positive role in the treatment of DF. |