The Experimental Research Of Micro-Suture Of Tendons Cooperated With Sodium Hyaluronate Preventing Tendon Adhesion

Objective:The postoperative tendon adhesion after injury is one of the familiar clinical puzzles.The prevention of tendon adhesion is also the significant task of hand surgery. Domestic and foreign scholars have done a massive of clinical and experimental researches, attempting to prevent or ease tendon adhesion, but as yet have not achieved ideal results. As we know, the tendons and the surrounding tissues both participate in restoration of injured tendons, namely endogenous and exogenous healing , and the exogenous healing processes have close relationship with scar adhesion. So that how to promote endogenous healing, restrain excessive exogenous restoration, to reduce scar adhesion maximally during restoration has become a new way of treating tendon injury. Our research observes the influence of micro-suture of tendon and micro-suture with sodium hyaluronate used locally upon tendon healing and postoperative adhesion and probes into clinical application value of micro-suture of tendon cooperated with sodium hyaluronate.Methods:1. Choose 48 common healthy New Zealand rabbits , male or female ,weight between 2.0-2.5 kg, divide them into 3 groups with 16 in each according to different operative method. Take toe tendon flexor digitorum profundus of bilateral hind limbs for experimental use. Take 3 % pentobarbital sodium for intravenous anesthetics, then expose and transect tendon m.