| Objective To assess the clinical effectiveness and safety of uvulopalatopharyngoplasty (UPPP) in the treatment of sleep related breathing disordersMethods We searched MEDLINE (1966-2005) , EMBASE (1984-2005), Cochrane Library ( Issue 1, 2005), CMB (1979-2005), CNKI( 1994-2005), VIP( 1989-2005), CMCC (1994-2005) ,Wangfang Datadbase and Internet . Only English and Chinese literatures were searched..Literature references were cheched intensively.Randomized controlled trials,quasi-randomized controlled trials and prospective cohort studies were identified. Study quality was evaluated by two researchers independently. RevMan4.2.7 was used for meta-analysis.Results Twelve studies were included and 5 were randomized controlled trials ,7 were prospective cohort studies. Compared with dental appliance (DA), DA group's PSG changes were larger than UPPP group, but the UPPP group had better quality of life and compliance. UPPP compared with... |