| Objective: To observe the effects of the Febricide and Catharsis Treatment of Chinese Medicine (FCTCM) to the Obstructive Jaundice Endotoxemia (OJE). Method: Experimental rats were divided into 4 groups: the Model Group (which also falls into two groups: one was treated with FCTCM and the other with the western medicine), the Model Control Group and the Blank Group. Make a mold through ligating the common bile duct of the Model Group and the Model Control Group rats. While, to the Blank Group rats, just pulled the common bile duct loosely, not to tie them up. Feeded the Model Group rats with experimental preparation-food. After the experiments ended, we examined the indexes of blood plasma endotoxin, TNF - α and the liver function of the rats in each group respectively, and manufacture their liver pathological slices. And analyzed the effect of the FCTCM treatment to the Obstructive Jaundice Endotoxemia of the rats including their TNF - α based on the experimental data. Results: After treated by the Febricide and Catharsis Treatment of Chinese Medicine, the rats, which are with the Obstructive Jaundice Endotoxemia, have improved their quality of fur color and temper, they obviously drinked more water daily than usual (P < 0.05), which droped each experiment index compared with the rats in the Model Contrast Group (P < 0.01). They also had a better improvement of TNF compared with the ones in the western medicine group (P < 0.05). They had got almost exact treatment effects (P > 0.05) of the rest experiment indexes and had got a much better improvement tendency to the rats in the western medicine group. All that indicates the FCTCM was not only effective to the treatment of the Obstructive Jaundice Endotoxemia, but also it was superior to the treatment for the rats in the Model Contrast Group with western lactose medicine. Conclusion: It is safe and effective to apply the FCTCM to the treatment for the Obstructive Jaundice Endotoxemia. |
PDF Full Text Request