| Objective: To investigate the correlation between pathologic features and ultrasonographic findings.Meanwhile to evaluate the correlation between estrogen receptor expression of infiltrating ductal carcinoma(IDC) and infiltrating lobular carcinoma(ILC) vs ultrasonographic findings, axillary lymphnodes metastasis and morphologic, and menopause state in breast cancer.Methods:Ultrasonographic scanning was performed in 88 patients with breast cancer before operation.Ultrasonographic morphologic features were analyzed.The mastectomy specimens were stained with immunohistochemistry, and the expression of ER was measured. The pathologic results were compared with ultrasonographic features.Results: Among the 88 breast cancer cases, 78 cases confirmed by pathology were positive .10 cases were not: 5 cases Of infiltrating ductal carcinoma, 3 cases Of infiltrating lobular carcinoma, 1 case Of medullary carcinoma, 1 case of apocrine carcinoma,and 1 case of inflammatory mammary carcinoma. Meanwhile, the expression of ER was significantly correlated with spiculate margin,posterior shadowing in infiltrating ductal carcinoma and infiltrating lobular carcinoma ( p<0.05 ) . Microcalcifications, axillary lymphnodes metastasis,pre- and post- menopause and size of breast tumor have not statistically significant difference with ER positive expression( (p >0.05) ). Conclusion: Ultrasonographic morphologic features exist some correlation with pathology and molecular biology factors in breast cancer to certain extent. The biologic behavior and prognosis can be assessed according to ultrasonographic features. |
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