Simulation Of Mitral Regurgitation Using Ultrasonic Doppler Flow Imaging

Mitral regurgitation (MR) is one of the most serious heart diseases. Color Doppler flow imaging is the most popular modality to quantitatively evaluate the complex mitral regurgitation because of its convenience, noninvasiveness and cheapness. But there have some problems in clinical application. Firstly, as the radiofrequency(RF) signals from ultrasound system are not available directly, the study on RF signals of mitral regurgitation is impossible;Secondly, it is difficult to estimate the blood velocity accurately duo to the angle between the ultrasound beam and blood flow. Thirdly, for the presence of disturbed flow and its complication, there is no field model for turbulent flow in the heart. Nowadays, although numerous echocardiographic techniques, both qualitative and semi-quantitative, have been proposed,no one is can be used as a"golden standard"for clinical quantitative evaluation of mitral regurgitation, especially the eccentric regurgitation. This study focuses on the simulation of the ultrasound Doppler flow imaging of mitral eccentric and central regurgitation, and it has significance to quantitatively assess mitral regurgitation clinically. There is no research report for this topic.Numerical models of mitral eccentric and central regurgitation based on the orifice shape, flow length and flow field of MR are proposed and the simulation of ultrasound Doppler flow imaging of mitral regurgitation is explored in this study. According to the model of round axial symmetry turbulence jet and 3 D turbulence jet,the central mitral regurgitation can be simply simulated by three types, that...