Objective: The aim of this study was to compare studying observe between lung cancer combined and non-combined Chronic Obstructive Pulmonary Disease (COPD) patients, and to evaluate the influence of COPD on postoperative pulmonary function, and to elucidate the factors for decreasing the reduction of pulmonary function after lobectomy.Materials and methods: After excluded those dissatisfying patients, 72 patients who had undergone lobectomy for non-small cell lung cancer at The First Affiliated Hospital Of Kun—Ming Medical Collage from 2004 to 2005 was enter to this study .Twenty patients were categorized as COPD, who defined according to our country 1997's Diagnose And Treatment Standard for COPD .The remaining fifty-two patients were categorized as non-COPD. Measure each patient's pulmonary function data , arterial blood gas analysis data , walk distance in 6 minutes and sick impact profile (SIP) before and early after lobectomy . After gain all scores , use SPSS 13.0 version statistical software to analysis these data.Results: Although all preoperative pulmonary function test data and arterial oxygen tension were significantly lower in COPD group , postoperative arterial oxygen tension and FEV1/FVC were higher than non-COPD group , and minimal deterioration of main item of PFT in COPD group than non-COPD group. The ratio of apoFEV1 to ppoFEV1 which was higher than 1.0 was significantly related with COPD and coefficient R was 0.596. With multivariable analysis ,COPD, the portion of pulmonary resection and patient's age were identified as independent factors for better... |