Experimental Research Of XiaoErTuiReJieDu Decoction (XETRJD) On Antipyretic And Anti-inflammatory Effect And Mechanism

Objective: External contraction fever is frequent and multiple disease of childhood, which has the features of falling ill urgently, changing quickly and short course etc, and it belongs to acute upper respiratory infection (AURI) in modern medicine. Its routine cure methods are to adopt medicine such as antibiotics, antipyretic, adrenal cortical hormone (ACH). But these medicines easily emerge drug resistance and adverse reaction of hypersensitiveness or gastrointestinal tract etc. But traditional medicines have obtained better curative effect on treating external contraction fever.External contraction fever belongs to cold in traditional medicine. My tutor regards that its mechanism owes to invading surface of wind-heat and poison, disease involving both weifen and qifen. So we use the methods of getting rid of wind-heat and poison, heat-clearing and detoxicating, purging pathogenic fire and pyretolysis for treating external contraction fever. In the direction of the methods and combining the modern rearch of herb pharmacological, we make the reasonable combined prescription of Chinese herbs-XiaoErTuiReJieDu decoction (HETRJD), which is composed of yinhua, lianqiao, chaihu,...