Preparation Techniques Of Silk Fibroin/ Gelatin Blend Membranes And Its Structure And Performance

Silk fibroin is an inartifical protein used as textile material for a long time. Now interests have risen in the use of silk fibroin as starting material for advanced biomedical applications such as wound dressing and artifical skin based on its avirulence and excellent biocompatibility. But pure silk fibroin film is frangibility and can be dissolved in water easily. To extend the use field of silk fibroin, people must search a fine method. Gelatin can be biodegraded easily and has excellent biocompatibility, but it is frangibility and often be eroded by bacteria in moist conditions. Now there is no satisfying produce in wound dressing field. To resolve these problems, gelatin were added into silk fibroin with different blending rates to make blend membranes. SF/G blend membranes were prepared by casting aqueous solution and dried at 40 "C, 60 °C and 80 °C for 4h,8h and 12h respectively. Then treated by different concentration ethanol aqueous to enhance the water resistively. The structures of SF/G blend membranes were tested by ESEM and FT-IR. And tested the performance of blend membranes by suitable methods. The main results are as follows: 1. Blend rates have best remarkable influence on swelling rate and water solubility rate of SF/G blend membranes. The SWR become higher with the gelatin rate in blend membranes rise, but WSR is opposition. But there is a critical gelatin rate. SFG4 has the highest SWR and the lowest WSR. Different concentration ethanol aqueous treatments also have best remarkable influence on swelling rate and water solubility rate of SF/G blend membranes. The blend membranes treated by 50% ethanol aqueous have highest SWR and lowest WSR. 2. Blend rates, dry temperature, dry time and different concentration...