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The Affection Of HuangQinZhengQi Capsule To Gastrointestinal Function Of The Disease Of Damp Blocking The Middle-jiao In Rat

Posted on:2006-07-25Degree:MasterType:Thesis
Country:ChinaCandidate:X H KongFull Text:PDF
GTID:2144360152998115Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
HuangQinZhengQi Capsule (HQZQC) is composed of affiliating Scutellaria baicalensis Georgi basing on BuHuanJinZhengQi Powder the representative prescription of balminess, dehumidification and activating spleen. HQZQC has the efficacy of dehumidification, eliminating turbidity, reconciling stomach and activating spleen. HQZQC is made for the disease of damp blocking the middle-jiao, mainly cure the symptom of slightly detesting the cold and low fever, or having a fever but no catharsis, the stomach is bulgy and vomit, thirst but not want a drink, halitosis and lingua is white or slight yellow, and the pulsation is logy etc.We have found that HQZQC has the function of accelerating the gastric eduction, strengthening the digestive ability of the stomach and intestines, protecting the gastric mucosa and resisting inflammation in natural rat or mouse in fore experimental research. Therefore, basing on fore experimental result, for exploring the affection HQZQC to the disease of damp blocking the middle-jiao, we are based upon the primary efficacy and primary remedial symptom of HQZQC, refer to literature search. We adopt the method that make high air temperature and high humidity for urging damp and turbidity and evil influence to be dense and suffocating for the sake of changing creatural habitation and simulating the outer waterish circumstance that results in illness, besides make animal take honey and lard orally for urging them to eatoverfull fat and sweetmeat, in addition compel animal to swim excessively for consuming plentiful physical strengthen this way depleting creatural righteous gas, scathing creatural spleen and stomach and blocking movement for making inner damp to copy the disease of damp blocking the middle-jiao in rat whose type is "outer damp invades clay+ righteous gas is exhausted+ eating overfull fat and sweetmeat" and study HQZQC' s affection to the disease of damp blocking the middle-jiao in rat.On the basis of finishing copying the disease of damp blocking the middle-jiao in rat whose type is "outer damp invades clay+righteous gas is exhausted+eating overfull fat and sweetmeat" ,we observe that HQZQC' s preventive and remedial function to the avoirdupois^ animal heat and dietetic amount as well as gastrointestinal function of the disease of damp blocking the middle-jiao in rat. The result indicates that HQZQC has definite preventive and remedial function to the disease of damp blocking the middle-jiao in rat takening orally according to 0.175^ 0. 35(h 0. 700g/kg (avoirdupois) . HQZQC can lower elevatory animal heat caused by the disease of damp blocking the middle-jiao, increase dietetic amount and avoirdupois of the disease of damp blocking the middle-jiao in rat, improve the condition of decreasing gastric juice> elevatory pH value of gastric juice and depressed activeness of pepsin caused by the disease of damp blocking the middle-jiao, besides increase gastrin content of the disease of damp blocking the middle-jiao in rat, strengthen alvine absorbency to D-xylose and movement, heighten the activeness of gastric mucosal protective gene-superoxide dismutse (SODK catalase (CAT) as well as improve the rat' s gastric> duodenal pathologic change etc caused by the disease of damp blocking the middle-jiao. The result has statistic significance (p<0.05-0.01) .It clues on that HQZQC has the function of increasing dietetic amount and avoirdupois, lowering animal heat of low fever, strengthening gastrointestinal digestant> absorptive and kinetic enginery, strengthening gastric mucosal protective ability as well as...
Keywords/Search Tags:HuangQinZhengQi Capsule, the disease of damp blocking the middle-jiao, creatural model, gastrointestinal function
PDF Full Text Request
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