| ObjectiveThrough the epidemiological investigation of the small sample of rural areas in Yanqing county of Beijing, we attempt to realize the epidemic situation and TCM syndrome features of prehypertention in the rural areas of Beijing outskirts, which could provide objective and scientific basis of prevention and treatment for hypertention and prehypertention not only in this region but also in the national rural areas.MethodsWe chosed cross-sectional survey method and selected the residents aged 40 to 75 of 31 administrative villages of Jingzhuang town of Yanqing county as the survey population with the way of cluster sampling selection. According to the related literature and results of previous research, we determine the criteria of diagnosis, inclusion and exclusion. Eventually, a total of 334 patients with prehypertention are put into the research and analysis as the research objects. We collected baseline information, relevant cardiovascular risk factors and tongue veins, symptom and TCM syndrome differentiation of research objects through inquiry, physical examination, testing blood samples and TCM four diagnosis and finally used Microsoft Excel 2007 and IBM SPSS Statistics 20.0 for data entry and analysis.Results1. In the 920 survey population, there are 381 patients suffering from prehypertention. So in this region, the standardized detection rate of prehypertention is 41.74%. Besides, the male’s standardized rate of prehypertention is 43.02% and the female’s standardized rate of prehypertention is 38.42%. The the detection rate of prehypertention in this region is higher than the national average level and decline along with the age growth. High-risk age of prehypertention is 50-59 years old, but the gender difference was not significant.2. During the research objects, the average SBP was 132.76±6.51mmHg, the average DBP was 82.41±4.86mmHg. The DBP level of male (133.23±5.80mmHg) is significantly higher than female (81.59±5.10mmHg), which is not found in SBP levels. the people whose SBP and DBP are all rise account for the highest proportion (72.16%), followed by people who only have high SBP (20.06%) and people who only have high DBP(7.78%). The average pulse pressure of research objects is 50.33±8.16 mmHg. People with nomal pulse pressure account for 94.91%, in which people with pulse pressure of 41-60 mmHg accounted for 89.59%. Pulse pressure is positively related with age and the pulse pressure of female is higher than that of male. People with grade two of prehypertention account for 95.21%, which is significantly more than people with grade one of prehypertention (4.79%).3. In the people aged 40-49, there are more women than men who suffer from prehypertention. The average BMI is 25.17±3.49 Kg/m2 and the average waist-size was 84.20±9.31cm. BMI level of the women is higher than men, the number of obesity patients decrease as age growing. There are a total of 190 people with abdominal obesity, of which the women’s proportion is larger than men. People with normal blood sugar account for 55.69%(186 cases), people who suffer from impaired fasting glucose account for 24.25% (81 cases), people who suffer from diabetis account for 20.06% (67 cases). Meanwhile, a significant positive correlation was found between blood glucose and the age. People with normal blood lipid account for 39.52%(132 cases) and dyslipidemia patients account for 60.48% (202 cases). Most of the dyslipidemia patients aged 50-59 and 60-69. Dyslipidemia are mainly composed of elevated TG and TC, patients with only one abnormal index (44.55%), patients with two abnormal index (33.66%), patients with three abnormal index (16.34%), pat ients with four abnormal index (5.45%). In the research objects, people who are smoking account for 25.15%, the proportion of people who are lack of physical activity is 38.62%, people with a family history of early onset of cardiovascular disease and stroke account for 26.65% and 15.87%. In the patients who are lack of physical activity, there are more women than men. In the patients who have a family history of early onset stroke,there are more men than women.4. The influence factors of systolic blood pressure include age, BMI, waist circumference, blood glucose, TG, TC, LDL-C, HDL-C and lack of physical activity, amomg which the increased BMI and blood glucose level are risk factors for systolic blood pressure and are significantly positively related with systolic blood pressure. The influence factors of diastolic blood pressure include gender (male), age, TG, TC and LDL-C, among which male and old age are risk factors for diastolic pressure and the age is significantly positively related with diastolic blood pressure.5. In the research objects, deficiency of gan-yin and shen-yin syndrome account for 42%, the number of is on the rise as age growing; intermingled phlegm and blood stasis syndrome account for 36%, the number of which decreases as age growing; stagnation of gan qi syndrome account for 22%. The main growing type of blood pressure is the simultaneous increase of SBP and DBP in all three syndromes. In every syndrome, the number of patients with overweight is the largest, following with normal people, obese patients and underweight people. In patients with abdominal obesity, the number of intermingled phlegm and blood stasis syndrome is the largest, following with deficiency of gan-yin and shen-yin syndrome and stagnation of gan qi syndrome. In all three syndromes, dyslipidemia are mainly composed of elevated TG and TC; in the patients of stagnation of gan qi syndrome and intermingled phlegm and blood stasis syndrome,the most outstanding aspect of dyslipidemia is the rise of TG,following with the rise of TC; while in the patients of deficiency of gan-yin and shen-yin syndrome, the most outstanding aspect of dyslipidemia is the rise of TC, following with the rise of TG. In the smoking population, deficiency of gan-yin and shen-yin syndrome is the most, following with intermingled phlegm and blood stasis syndrome and stagnation of gan qi syndrome.Conclusion1. The the detection rate of prehypertention in this region is higher than the national average level and decline along with the age growth. High-risk age of prehypertention is 50-59 years old, but the gender difference was not significant.2. In this region, most of people belong to grade two of prehypertention and the blood pressure rise as age growing. The main growing type of blood pressure is the simultaneous increase of SBP and DBP. The DBP level of male is significantly higher than female, which is not found in SBP levels.3. In this region, the bodily form of people who suffer from prehypertention is fatter and women’s proportion of abdominal obesity is larger than men. People with sugar metabolic abnormalities account for nearly half and a significant positive correlation was found between blood glucose and the age. Dyslipidemia are mainly composed of elevated TG and TC, patients with only one abnormal index (44.55%), patients with two abnormal index (33.66%), patients with three abnormal index (16.34%), patients with four abnormal index (5.45%). In the research objects the proportion of people who are lack of physical activity is about one third,of which women is more than men; people who are smoking and have a family history of early onset of cardiovascular disease account for about a quarter; people who have have a family history of early onset of stroke account for about one fifth, of which men is more than women.4. The influence factors of systolic blood pressure include age, BMI, waist circumference, blood glucose, TG, TC, LDL-C, HDL-C and lack of physical activity, amomg which the increased BMI and blood glucose level are risk factors for systolic blood pressure and are significantly positively related with systolic blood pressure. The influence factors of diastolic blood pressure include gender (male), age, TG, TC and LDL-C, among which male and old age are risk factors for diastolic pressure and the age is significantly positively related with diastolic blood pressure.5. In the research objects, deficiency of gan-yin and shen-yin syndrome account for 42%, the number of is on the rise as age growing; intermingled phlegm and blood stasis syndrome account for 36%, the number of which decreases as age growing; stagnation of gan qi syndrome account for 22%. The blood pressure, body size, sugar metabolism and lipid metabolism disorder characteristics of each syndrome are similar with the whole population with prehypertention. In the smoking population and people with high TC and LDL-C, deficiency of gann-yin and shen-yin syndrome is the most, following with intermingled phlegm ad blood stasis syndrome and stagnation of gan qi syndrome. |
PDF Full Text Request