Study On The Characteristics Of TCM Syndrome And Syndrome Distribution Of Reflux Esophagitis

Reflux esophagitis (RE) is inflammation of the esophagus mucosa lesions, mainly is caused by excessive exposure or contact with gastric juice, more manifest heartburn and acid reflux, still can cause not a typical extraesophageal symptoms,such as throat unwell, difficulty swallowing, chronic pharyngitis,which can easily lead to misdiagnosis. With modern life rhythm speeding up and stress increase, the incidence of reflux esophagitis is rising.ObjectiveAnalysis traditional Chinese medicine(TCM)syndrome type of RE and the relationship with the sex, age, etiology and so on,then discusses the law of TCM syndromes, to provide certain reference basis to individualized treatment of the disease.MethodsThis thesis includes literature review and clinical research.Literature review is divided into two articles. First article is discuss reflux esophagitis in modern medicine research, mainly includes the basic and clinical research progress of the RE. It include the etiology, pathogenesis, clinical manifestations, diagnosis and treatment and so on. The second one is discuss reflux esophagitis in traditional Chinese medicine. It discusses the naming, pathogenesis, syndrome differentiation and syndrome differentiation and treatment and so on.Clinical research parts:first, make case roport form by reference to western medicine diagnostic criteria and and collect 130 cases from the third affiliated hospital of Beijing University of Chinese Medicine and the Eastern hospital of Beijing University of Chinese Medicine. Second, we collect general information, history of present illness, gastroscope report, and syndromes to type-in excel. Finally, using the factor analysis method by using SPSS 20.0 statistical software, to discuss common syndromes, syndrome element distribution characteristics of RE.Results(1) There is no significant gender differences in incidence of the disease and the higher prevalence was middle-aged people. (2)This research shows that the risk factors of reflux esophagitis is alcohol and tobacco, mental pressure, constipation, poor eating habits. Risk factors is different in different ages. Young patients with predominantly mental stress and poor diet, middle-aged and old is given priority to with alcohol,tobacco, strong tea, constipation. (3) By using clustering analysis, we can conclude that symptom elements of disease location are stomach, spleen, liver, the nature of the disease syndrome elements is qi deficiency, qi stagnation, wet, hot; Similar syndrome can be roughly divided into:similar spleen-stomach deficiency, similar stagnation of liver qi and stomach qi, similar stagnated heat of liver and stomach, similar spleen deficiency and hot-humid. (4) By using factor analysis method, a preliminary concluded that the disease common TCM syndrome type:liver-gallbladder damp and heat, similar spleen-stomach deficiency, similar stagnation of liver qi and stomach qi, similar stagnated heat of liver and stomach, similar thriving liver fire.Conclusion(1) By cluster analysis and factor analysis of reflux esophagitis to discusses the four diagnostic information research, preliminary reached the that symptom elements of disease location are stomach, spleen, liver, the nature of the disease syndrome elements is qi deficiency, qi stagnation, wet, hot. The qi stagnation(37.69%) of liver qi and stomach qi and spleen deficiency and damp and heat(27.69%)for a larger proportion. (2)The results of factor can react characteristics of the distribution of syndromes and syndrome factor really,which can avoiding the traditional research method caused by too much subjective factors in the role, objectively reflect characteristics of the distribution of TCM syndromes and syndrome elements of RE, to provides an important reference value for the diagnosis and treatment of this disease.