| Background:Benign Prostatic Hyperplasia is a middle-aged and old male common disease, frequently-occurring disease, its incidence increased year by year, with higher standards of living in 50% generally 50-60 year-old male pathologic hypertrophy of the prostate, can be as high as More than 90% at the age of 80. An enlarged prostate can oppression urethra, make urethral stricture, appear dysuria, urinary, appear serious urinary retention, such as obstruction time is too long can lead to kidney damage, even life-threatening;BPH has become the international focus on major diseases. Prostatic hyperplasia belongs to traditional Chinese medicine on the category of "retention of urine" and "fine Long". The third affiliated hospital of Beijing medical university male urinary based on the clinical theory, adopting top uroschesis tong tablets combined western medicine treatment of kidney and blood stasis syndrome of benign prostatic hyperplasia, micturition symptoms, improve quality of life in improving patients achieved remarkable curative effect.Objectives:Research QianLieLongBiTong troche and Tamsulosin Hydrochloride Sustained Release Capsules treats kidney deficiency and blood stasis type of benign prostatic hyperplasia inclinical research. Observes QianLieLongBiTong troche and Tamsulosin Hydrochloride capsule to treat this disease the clinical effectiveness and safety.Methods:With the randomized, controlled clinic tri research method, the selection of patients with BPH 87 cases, into two groups, indicating that the treatment group and control group, treatment group 44 cases, control group 43 cases. the treatment group with QianLieLongBiTong troche and Tamsulosin Hydrochloride capsule, the control group was Tamsulosin Hydrochloride capsule. 1 months for a period of treatment, observe a course of three. After three treatments (3 months) after treatment, which we assess the therapeutic effects by observing the improvements of the TCM Syndrome marks,the international prostate symptom score (I-PSS), voiding symptoms on quality of life (QOL), Prostate volume, residual urine volume, maximum urof low rate changes of detection before and after the treatment. All results are statistically analyzed with SPSS19.0,and P<0.05 show there is a significant difference, having statistical sense.Results:In the treatment group 42 cases of patients, The cure rate was 21.88%, the rate of the marked effective cases was 53.13%,the rate of effective cases was 21.88%. and the rate of inefficacy was 3.13%,The rate of total effective was 96.87%; compared to control group 42 cases of patients (Display the cure rate was 6.25%, the marked efficiency rate was 25.0%,the effective rate was 46.88%,the inefficacy rate was 21.88%, The total effective rate was 78.12%), the total significant difference has statistical sense (P<0.05),In the areas of the TCM Syndrome marks, the international prostate gland symptom grade (I-PSS) the urination symptom to quality of life(QOL) influence, residual urine volume(RUV), maximum uroflow rate (MFR), both groups show significant improvements after the treatment (P<0.05). in the prostate mass than two groups, the treatment group on narrowing prostate volume has certain effect (P<0.05), and the control group to prostate volume without change, the difference was not statistically significant (P>0.05).Conclusion:the QianLieLongBiTong troche and Tamsulosin Hydrochloride capsule was effective in-the treats kidney deficiency and blood stasis type of benign prostatic hyperplasia and could enhance the efficacy of the cure rate and manifest improvement rate, reduce IPSS integral, improve the quality of life of urination symptoms affect, improve the quality of life of the patients, reduce symptom scores of traditional Chinese medicine, reduce prostate volume,especially for those people with obvious urinary symptoms; As a treatment for the disease can be a good choice. |
PDF Full Text Request