Research On Epidemiological Issues Related To COVID-19 Prevention And Control In Large Labor-intensive Enterprises During The Different Periods Of The COVID-19 Epidemic

ObjectiveTo investigate exposure history,travel history,health service needs,the level of knowledge,attitudes,and practices(KAP),and mental health status among employees during the different periods of the coronavirus disease 2019(COVID-19)epidemic,and the coverage of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccination and the willingness to receive the SARS-CoV-2 variant strain vaccine during the longer-term stage of the COVID-19 epidemic.Furthermore,to explore the influencing factors of different outcomes during different periods of the COVID-19 epidemic.Based on these results,we aimed to provide scientific evidence for identification and management of high-risk people,allocation of health resources,health education,mental health services,and vaccination.MethodsTwo rounds of epidemiological surveys were conducted among employees in a large labor-intensive enterprise in Shenzhen during the early stage(February to April 2020)and the longer-term stage(January to February 2022)of the COVID-19 epidemic,respectively.Frequency and percentage were used to demonstrate the exposure history,travel history,the prevalence of KAP level,mental health status,and the vaccination coverage and willingness.Bidirectional elimination Logistic regression models were used to estimate the associations of epidemic-related factors and demographic factors with different outcomes.Results(1)The prevalence and change of different indicators during the early stage and the longer-term stage of the COVID-19 epidemicA total of 137930 and 62395 participants were included during the early stage and the longer-term stage of the COVID-19 epidemic,respectively.16030 employees lived in Hubei Province in last two weeks,and 2922 employees had confirmed cases around them in the early stage of the COVID-19 epidemic.Disposable medical masks and thermometer are the most needed protective equipment for employees.Compared with the scores in the early stage of the COVID-19 epidemic,the scores of knowledge and attitudes increased from 77.90 to 79.19 and 82.50 to 85.86 in the longer-term stage of the COVID-19 epidemic,while the scores of practices decreased from 92.60 to 88.08.The prevalence of anxiety symptoms and depression symptoms increased from 3.2%to 6.8%and 22.0%to 40.0%,respectively.When participants were restricted to those who have the same identification number between the two rounds of surveys,similar trends were observed.As of January 30,2022,the rate of SARSCoV-2 vaccination was 98.9%,and 97.7%of the participants had willingness to receive the SARS-CoV-2 variant strain vaccine.(2)The influencing factors of different outcomes during the early stage of the COVID-19 epidemicThe results of multivariate Logistic regression analysis showed that the education duration of 7 or more years,age of 25 or more years,actively participating in physical exercise,cumulative confirmed cases of 1000 or more in the living region,and higher positions in the enterprise were positively associated with a good level of KAP,as well as absence of anxiety symptoms and depression symptoms.Having suspected cases,confirmed cases or unknown infectious people around,general or poor health status,and living in rural areas were associated with a poor level of KAP,as well as anxiety symptoms and depression symptoms.Sleep duration of less than 7 hours or more than 11 hours every day,and more alcohol consumption were positively associated with anxiety symptoms and depressive symptoms,and employment duration of 7 or more months was associated with anxiety symptoms.(3)The influencing factors of different outcomes during the longer-term stage of the COVID-19 epidemicThe results of multivariate Logistic regression analysis showed that the education duration of 7 or more years,age of 25 or more years,actively participating in physical exercise,and higher positions in the enterprise were positively associated with a good level of KAP,as well as absence of anxiety symptoms and depression symptoms.Being suffered from violence,and general or poor health status were associated with a poor level of KAP,as well as anxiety symptoms and depression symptoms.Sleep duration of less than 7 hours or more than 11 hours every day,more alcohol consumption,and employment duration of 7 or more months were associated with anxiety symptoms and depressive symptoms.Longer education duration was positively associated with having received SARS-COV-2 vaccine and had a willingness to receive the SARS-CoV-2 variant strain vaccine.General or poor health status,and having no history of influenza vaccination were inversely associated with having received SARS-COV-2 vaccine and had a willingness to receive the SARS-CoV-2 variant strain vaccine.ConclusionThe knowledge and attitudes of participants on the COVID-19 epidemic improved,but their prevention practices become lax from the early stage of the epidemic to now.The prevalence of anxiety symptoms and depression symptoms significant increased.Additionally,we observed an enough high rate of SARS-CoV-2 vaccination and willingness to receive SARS-CoV-2 variant strain vaccine among enterprise employees.Epidemic-related factors and demographic factors,such as age,education duration,health status,physical activity,violence treatment and position had prominent effects on different health outcomes.Relevant strategies according to these factors should be developed and implemented in time.