| Lung Cancer is a serious illnesses that caused under long-term exposure to risk factors, bronchial epithelial cells or alveolar epithelial cells mutate the gene to produce uncontrollable proliferation, and thus brings a number of symptoms. Due to various reasons include the acceleration of the expansion of urbanization and industrialization of production, worsening air pollution, the presence of factors were partially occupational exposure, and smoking crowd not controllable, the incidence and mortality of lung cancer present a lot of growth compared to the past and become a serious social problem. Patients of lung cancer with early stage are generally treated with surgery. However, surgery is not suitable in patients with late stage, but for radiotherapy or chemotherapy. The chemotherapy treatments have serious adverse effects, seriously affecting the quality of life of lung cancer patients. Tradition Chinese Medicine believes that while damage righteousness chemotherapy are evil, and lung cancer patients themselves physical weakness, strength is more damage to internal organs, and blood deficiency, resulting in toxicity. Moxibustion therapy is one of the traditional Chinese medicine external treatment, give full play to the role of the meridian of specific treatment, the body regulating yin and yang balance. The ginger moxibustion therapy is one kind of Moxibustion, combined with the effects of ginger Jiangni and treatment of gastric and Xinwen potency and moxibustion. Sihua acupoints are a group of four acupuncture points for the combination of traditional moxibustion treatment, with tune up blood, eliminate TB tonic, qi Chest, Jiangni vomiting, blood analgesic effect. The role of the side effects of chemotherapy in lung cancer patients has generated great significance. Therefore, to explore ginger moxibustion on points to improve to improve the adverse effects of chemotherapy and prevention of lung cancer patients, with good clinical practice.Objective:In this study, a randomized controlled clinical trial designed to explore the ginger moxibustion Sihua point therapy to improve the treatment of lung cancer patients after chemotherapy KPS, QOL score, vomiting and other side effects, as well as resistance to chemotherapy observed moxibustion bone marrow suppression.Method:All the patients are collected from Baiyun Branch of Second Guangdong Hospital of Chinese Medicine and Huang Pi hospital. Patients collected meets the diagnostic criteria and inclusion criteria, and to meet the exclusion criteria of cases removed, the final collection of standards and advanced lung cancer research standards (III stage, IV stage) total number of samples in patients60patients were randomly divided into treatment group and control group of30patients, found no cases of exclusion criteria break after the end of the test. All of the groups of lung cancer patients according to their actual situation were appropriate choice of chemotherapeutic drugs from conventional chemical anticancer therapy combined with chemotherapy in the three groups. Treatment group from three days before the start of chemotherapy spend four points ginger moxibustion treatment, spent four points using a more generic bladder full sun located on the back side of the first line Geshu and bile shu, moxibustion8each per hole strong, once a day, until14days after treatment with chemotherapy. Control group was not Ginger moxibustion therapy, conventional Western medicine only symptomatic and supportive treatment for the side effects of chemotherapy. Respectively, in the first day and14days of chemotherapy for all patients and control groups were KPS score the quality of life and quality of life QOL score, grading evaluation conducted vomiting after chemotherapy, after chemotherapy peripheral blood leukocyte count, the number of neutrophils, red blood cell count and platelet count, blood tests, and to evaluate the significance of these indicators.Results:1. A treatment group and the control group before the start of the test gender, age composition, the first day of KPS scores and other contrast after chemotherapy were not significantly different (P>0.05), consistent baseline comparable.2. After Ginger moxibustion treatment on points, the first14days of chemotherapy treatment group of KPS score and the first day was no significant difference (P>0.05), while the control group at14days of KPS score is compared to day1decreased significantly (P<0.05), the difference between the treatment group and the control group was statistically significant (P <0.05).3. After Ginger moxibustion treatment group spent four point processing, grading evaluation vomiting after chemotherapy was significantly better than the control group (P<0.05).4. After Ginger moxibustion treatment on points, the first14days of chemotherapy treatment group, the QOL score and the first day was no significant difference (P>0.05), while the control group at14days of QOL scores compared to the first day of the decreased significantly (P<0.05), the difference between the treatment group and the control group was statistically significant (P<0.05).5. Compare no significant difference between the treatment group and the control group of white blood cells before and after chemotherapy, neutropenia, hemoglobin, platelet and other indicators of change group (P>0.05).Conclusion:Relative to Western medicine symptomatic and supportive treatment, the treatment group after Ginger moxibustion on points after the KPS can significantly improve lung cancer patients after chemotherapy, QOL score, improve vomiting after chemotherapy, significantly improved the quality of life of lung cancer patients after chemotherapy, although not yet observed effects of ginger moxibustion on points on four indicators of bone marrow suppression after chemotherapy (leukocytes, neutrophils, hemoglobin, platelets), but ginger moxibustion four points can spend a short time to improve the prevention of chemotherapy and bone marrow suppression as in cause a variety of symptoms, with good clinical value. |
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