Construction And Evaluation On Medication Review System Of Community Elderly Patients With Chronic Diseases

With the population aging process continues to accelerate, the health of theelderly and the rational use of drugs are more important.Elderly physiologicaldysfunction and comorbid with a variety of diseases, often multipath department visits,multi-drug use and complex medication,which is prone to adverse drug reactions andother drug related problems (DRPs), a serious impact on the health and quality of lifeof older persons.However, effective intervention strategies are uncommon. Thepharmacist-led medication review interventions abroad are widely used to reduce thenegative events of the older medication, to improve medication income.In this study,use the method of systematic review, sample survey, quasi-experimental research onthe necessity and feasibility of medication review in China conducted a thorough andmeticulous research, mainly consists of three parts:Firstly, Systematic review the effect of domestic and foreign intervention trial onthe related issues of community elderly patients with chronic medication from2001-2010. The results show that pharmacist-led medication review(MR) can play animportant role in the identification, assessment and prevention of potential DRPs inthe elderly. No significant impact on the MR to improve the quality of life, reducinghospitalization and mortality.Secondly, the study took416case of community elderly polypharmacyout-patients in Shijiazhuang city for example, in-depth investigated the popularfeatures of their medications, explored the impact of taking potentially inappropriatemedications to adverse drug reaction(ADR). The results showed that with the numberof medication increased the prevalence of potentially inappropriate drugs increasedtoo,meanwhile the incidence of drug interactions and ADR also increases.Thepolypharmacy elderly feel more anxiety which make the drop of quality of life.Finally, according to the results of SR and baseline survey, build a medicationreview tools-TMRCE.Randomized controlled trials showed that TMRCE have abetter effectiveness and feasibility to reduce the potential risk of eldly medication.Itis worth to promote the use of medication review tools TMRCE.