Smoking Is The Relationship Between Insulin Resistance And Its Molecular Mechanism

Objective:To investigate the relationship between cigarette smoking and metabolic syndrome. Methods:Questionnaire and 75 gram oral glucose tolerance were conducted during a cross sectional study with clustering sampling in the citizens of Chongqing. Meanwhile glucose, lipid-profile, insulin, body weight, body height, waist circumference and blood pressure were measured. Results:â‘ Among 887 selected normal people, High-density- lipoprotein cholesterol(HDL-C), body mass index (IBM) , waist-hip ratio (WHR), body weight, waist circumference, triglyceride (TG), low-density- lipoprotein cholesterol(LDL-C) in smokers were higher than those in non-smokers.â‘¡The occurrence was higher in smokers than that in non-smokers including diabetes mellitus, impaired glucose tolerance (IGT), impaired fasting glucose (IGF), hypertension, lipid disorder, over weight /obesity and central obesity under 40 years old, the same as overweight/obesity, central obesity, high TG, low HDL-C from 40 to 60 and metabolic syndrome over 60 years old with the age-stratified among 3379 citizens.Conclusion:Cigarette smoking was one of the environmental factors which promoted the occurrence and development of metabolic syndrome.