The Clinical Observation Of Gua Sha Therapy Combined With Xuanfeizhike Decoction On Syndrome Of Wind-cold Staying At Lung Of Post-infections Cough

[Objective]To take guasha therapy for clinical intervention on patients with syndrome of wind-cold staying at lung of post-infections cough after lung infection.To observe the effects of guasha therapy on patient's syndrome,quality of life and levels of substance P in sputum,the characteristics and regularity of the image and positive reaction after scraping.To determine the therapeutic efficacy and safety of the technology.To formate a standardized operation scheme of guasha therapy for patients with syndrome of wind-cold staying at lung of post-infections cough after lung infection,and to provide scientific basis for clinical application and research.[Methods]For a randomized controlled trial design,this study take the convenience sampling method,select 90 cases of outpatients in Department of respiration of Jiangsu Province Traditional Chinese Medicine Hospital in accordance with the selection criteria,according to the table of random number.The patients are randomly divided into drug group(group A),guasha group(group B)and combination group(group C),30 cases in each.Group A is given Xuanfei Zhisou decoction,the man ingredients are ephedra,almond,ginger,platycodon grandiflorum,coltsfoot flower,pinellia,radix stemonae,su leaf,etc.l agent daily,half in morning and half in night,1 week for a course.Group B is given guasha therapy for once a week,1 week for a course.Scraping the bladder meridian,lung meridian,conception vessel and governor vessel on patients' back and abdomen,point scraping Taiyuan,Fengchi,Dazhui,ect.Group C is treated with guasha therapy combine with Xuanfei Zhisou decoction.The three group are treated for 2 courses.Before and after the intervention,the clinical efficacy,substance P in sputum and scores of Leicester Cough Questionnaire(LCQ)are compared.[Results]2 cases in Group A are excluded for taking other drugs.3 cases in group B are lost.So there are 85 cases complete the study,28 cases in group A,27cases in group B and 30 cases in group C.The baseline datas of the three groupsshow no statistically significant difference(p>0.05).After the intervention1.Comparsion between groups:(1)The cough symptom score,time of cough relivation,cough recurrence,cough degree(VAS)of the three groups show statistically significant difference(p<0.05),group C is the best(p<0.05).There is no statistically significant difference between group A and group B(p>0.05).The clinical effect of group A,group B,group C are 82.14%,81.48%and 96.70%.(2)The levels of SP in sputum supernatant of three groups are statistically significant(p<0.05),group C is better than the other 2 groups(p<0.05).There is no statistically significant difference between group A and group B(p>0.05).(3)The scores of LCQ of three groups are statistically significant(p<0.05).Group C is better than the other 2 groups in improving the quality of life(p<0.05).There is no statistically significant difference between group A and group B(p>0.05).(4)The comparsion of fever and positive reaction after guasha:after the first guasha therapy,fever is concentrated in the bladder meridian,lung meridian,conception vessel,governor vessel,Feishu,and Fengmen in group B and group C.Frepuency of the top 5 are Feishu,governor vessel,bladder meridian,lung meridian and Fengmen.Postive reaction is concentred in the bladder meridian,lung meridian,Baihui,Fengmen,Fengchi.Frepuency of the top 5 are Fenchi,bladder meridian,lung meridian,Baihui and Fengmen.After the second guasha therapy,fever and positive reaction are decreased in group B and group C.There are no statistically significant differences of fever and positive reaction between group B and group C(p>0.05).2.Group comparision:(1)The scores of cough symptom,time of cough relivation,cough cough degree(VAS)of the three groups are all decreased after intervation,the difference are statistically signifcant(p<0.05).(2)The sputum supernatant of SP of three groups are all decreased after intervation,the difference are statistically significant(p<0.05).(3)The scores of LCQ of the three groups are all improved after intervation,the difference are statistically significant(p<0.05).(4)The fever and positive reaction of group B and group C are less than before intervation,the difference are statistically significant(p<0.05).[Conclusions]1.Gua sha therapy can improve patients with cough symptoms and it is effect,safe and feasible.2.Guasha therapy can decrease the concentration of sputum supernatant of SP in patients with cough after infection.3.Guasha therapy can improve the patients' life quality.4.The combination of guasha therapy and Xuanfei Zhisou decoction is better than single drug or single guasha therapy in the treatment of cough after intervation.5.The fever and positive reaction report the etiology and pathogenesis,forecast the development trend of the disease.There may be some relationship between the symptoms and fever and positive reaction.