| Objective: By comparing the gastrointestinal and systemic symptoms as well as physical and chemical indexes of peritoneal dialysis patients and hemodialysis patients,it is discussed that peritoneal dialysis patients have a series of gastrointestinal and systemic symptoms due to the long-term retention of peritoneal dialysis fluid,which leads to the dampness of the spleen and leads to a series of gastrointestinal and systemic symptoms,and the causes of gastrointestinal complications of peritoneal dialysis are discussed from the perspective of traditional Chinese medicine.It provides theoretical basis and therapeutic idea for TCM treatment of gastrointestinal complications of peritoneal dialysis and improvement of dialysis adequacy.Material and methods: In this study,a total of 55 patients with peritoneal dialysis in the peritoneal dialysis Clinic of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from June 2022 to November 2022 and maintenance hemodialysis in the Blood Purification Center meeting the inclusion criteria were selected as research objects,including 30 patients with peritoneal dialysis and 25 patients with hemodialysis.Patients in the two groups were divided into A(12-18 months),B(19-24 months)and C(31-36 months)groups according to the dialysis age.TCM symptom scale was scored at the first,third and sixth months of the study.The scale scores and physical and chemical indexes of patients in the two groups were collected and a database was established with Excel software.SPSS27.0statistical software was used for data analysis.P < 0.05 was considered statistically significant.Results:1.Scale score analysis: at 1,3 and 6 months in group A,there were statistical differences between peritoneal dialysis group and hemodialysis group in gastric system,whole body and total score(P < 0.05),indicating that peritoneal dialysis group had obvious symptoms,while enteral system score had no statistical difference(P > 0.05).At 1,3 and 6 months,there were statistical differences between the peritoneal dialysis group and hemodialysis group in gastric system,whole body and total score(P < 0.05).There were no statistical differences in intestinal system scores at 1 and 3 months(P > 0.05),but there were differences at 6 months(P < 0.05),indicating that intestinal symptoms changed significantly with the increase of dialysis age.At 1,3 and 6 months,there were statistically significant differences in gastric,intestinal and systemic scores and total scores between peritoneal dialysis group and hemodialysis group(P < 0.05),indicating that symptoms in peritoneal dialysis group were more significant than those in hemodialysis group.2.In the comparison of individual symptom scores,there were no statistical differences in belching,acid reflux,stomach sobbiness,abdominal pain,diarrhea,ais,constipation,fatigue,dizziness,and zentaixi(P >0.05);stomach pain,stomach bloating,early satiety,nausea,poor appetite,abdominal distention,bowel sound,weak mouth,chest tightness,shortness of breath,sleepiness,limb weakness,limb sleepiness,and yellowish complexion(P < 0.05),and the peritoneal dialysis group was significantly higher than that in the hemodialysis group.2.Analysis of physical and chemical indexes: There were no statistical differences in leukocyte,erythrocyte,hemoglobin,platelet,total cholesterol,calcium,phosphorus,blood urea nitrogen,serum creatinine,blood uric acid,ferritin,triglyceride and parathyroid hormone in groups A,B and C at 1,3 and 6 months(P > 0.05).3.Analysis of albumin and prealbumin: There was no statistical difference between albumin and prealbumin in group A at 1 and 3 months(P > 0.05),but there was a difference between the two groups at 6 months(P < 0.05),indicating that the albumin and prealbumin levels in peritoneal dialysis group were lower than those in hemodialysis group at 6 months.Moreover,there were statistical differences in albumin analysis between the same group and the same group at 1 and 6 months(P < 0.05),indicating that albumin level in the peritoneal dialysis group decreased with the increase of dialysis age.There were no significant differences in albumin and prealbumin in group B at 1 month(P > 0.05),but there were differences in the data at 3 and 6 months(P < 0.05),indicating that the levels of albumin and prealbumin in peritoneal dialysis group were lower than those in dialysis group with the increase of dialysis age.There were statistically significant differences in albumin analysis between the same group and the same group at 1 and 6 months(P < 0.05),indicating that albumin level in the peritoneal dialysis group decreased with the increase of dialysis age.The data of group C at 1,3 and 6 months were different between the two groups(P < 0.05),indicating that the albumin and prealbumin levels in peritoneal dialysis group were lower than those in hemodialysis group.Conclusion: The results of this study showed that peritoneal dialysis patients had the situation of water trapping the spleen due to long-term retention of peritoneal dialysis fluid,which led to a series of gastrointestinal and systemic symptoms. |
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