Study On The Relationship Between TCM Syndrome Types, Quality Of Life Scores And Frailty In Elderly Patients With Hypertensio

Purpose: In this study,elderly patients with hypertension were taken as the research objective,frailty screening and life quality assessment were carried out to observe the distribution rule of TCM syndrome types,and explore the relationship between TCM syndrome types and life quality scores and frailty in elderly patients with hypertension.Method: The method of cross-sectional investigation was adopted to collect elderly hypertension patients from the dry diagnosis/geriatrics department of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,the dry diagnosis and rehabilitation department of cardiovascular medicine and rehabilitation center,and the department of cardiac rehabilitation and other departments in Shenyang City,Liaoning Province.The patients were screened according to the natrol standard.According to the Guiding Principles for Clinical Research of New Chinese Medicines(2002 edition)and the Guidelines for the Diagnosis and Treatment of Hypertension in Traditional Chinese Medicine,combined with the clinical practice,the included patients were classified into TCM syndrome differentiation,and the Fried frailties phenotype scale recommended by the Chinese Expert Consensus on Frailties Assessment and Intervention in Elderly Patients was selected for frailties screening.Patients were scored on quality of life based on the Concise Health Survey(SF-36),Clinical data were collected,including gender,age,education,income,BMI,number of comorbidities,grip strength,nutritional status,MHR,high density lipoprotein(HDL-C),low density lipoprotein(LDL-C),total cholesterol(TC),triglyceride(TG),etc.The collected data were input into Excel 2019,collated and collated,and imported into SPSS 26.0 software to statistically analyze the relationship between TCM syndrome type,quality of life score and frailty in elderly hypertension patients.Results:1.The distribution pattern of TCM syndrome types in elderly hypertension patients was as follows: excessive accumulation of phlegm-dampness(50%)> excessive liver-yang(24%)>excessive Yin and Yang(14%)> deficiency of Yin and Yang(12%).2.The quality of life score of elderly patients with hypertension was as following: overall score was(52.68 ± 22.59),PCS score was(49.29 ± 25.65)and MCS score was(56.06 ±21.75).3.Frailty in elderly patients with hypertension: frailty(64%)> pre-frailty(25%)> non-frailty(11%).4.There were significant differences in the distribution of TCM syndrome types in different asthenia groups of elderly hypertension patients(p < 0.05).Excessive accumulation of phlegm-dampness was the highest in the pre-asthenia group and the asthenia group.The detection rate of hyperactivity of liver Yang was negatively correlated with the prevalence of asthenia,while excessive accumulation of phlegm-dampness was positively correlated with the prevalence of asthenia.5.There were statistically significant differences in economic income,nutritional status,grip strength,number of comorbidity,PCS and MCS scores in different groups of elderly hypertension patients(p < 0.05).The number of comorbidity was positively correlated with the prevalence of frailty,while economic income,nutritional status,grip strength,PCS score and MCS score were negatively correlated with the prevalence of frailty.6.PCS and grip strength may be independent protective factors of whether elderly hypertension patients are complicated with fthenia,and the number of comorbidity may be independent risk factors of whether elderly hypertension patients are complicated with fthenia.7.There were significant differences in age,BMI and grip strength among different TCM syndrome types in elderly hypertension patients(p < 0.05).In the order of age from small to large,the syndrome of excessive liver-yang(68.15±3.55)< excessive accumulation of phlegm-dampness(72.92±6.26)< excessive Yin deficiency and Yang deficiency(74.71±4.12)< deficiency of Yin and Yang(87.93±5.24).The patients with excessive phlegm-dampness syndrome had the highest BMI and the patients with excessive liver-yang syndrome had the highest grip strength.8.There were statistical differences in the scores of PCS and MCS among different TCM syndrome types in elderly hypertension patients(p < 0.05).The scores of patients with hyperactivity of liver Yang syndrome were the highest,while those with deficiency of Yin and Yang syndrome were the lowest.9.Among TCM syndrome types of elderly hypertension patients,hyperactivity of liver Yang was negatively correlated with age and BMI,and positively correlated with grip strength,PCS and MCS.Excessive accumulation of phlegm-dampness was positively correlated with BMI.The syndrome of Yin deficiency and Yang hyperactivity was positively correlated with age and negatively correlated with BMI.The deficiency syndrome of Yin and Yang was positively correlated with age,but negatively correlated with TG,PCS and MCS.Conclusion:1.The distribution of TCM syndroms in elderly hypertension patients was dominated by accumulation of phlegm-dampness,low overall quality of life score and high incidence of frailty;2.PCS and grip strength were independent protective factors for senile hypertension patients complicated with asthenia,and the number of comorbidity was an independent risk factor for senile hypertension patients complicated with asthenia.The prevalence of asthenia in senile hypertension patients was negatively correlated with the diagnosis rate of hyperactivity of liver Yang,positively correlated with the diagnosis rate of accumulation of phlegm-dampness,and negatively correlated with MCS.3.There were significant differences in age,BMI,grip strength,PCS and MCS scores among different TCM syndrome types in elderly hypertension patients.Hyperactivity of liver Yang was significantly negatively correlated with age and BMI,but positively correlated with grip strength,PCS and MCS.There was a significant positive correlation between excessive phlegm-dampness obstruction and BMI.The syndrome of Yin deficiency and Yang hyperactivity was positively correlated with age and negatively correlated with BMI.Yin-yang deficiency syndrome was positively correlated with age,but negatively correlated with TG,PCS and MCS.