Clinical Observation On The Efficacy Of The Stroke Progress Prescription On Phlegm And Blood Stasis Obstruction Syndrome In Patients With Cerebral Infarction With Perforating Artery Diseas

Objective:To observe the clinical effect of apoplexy progression prescription on progressive cerebral infarction with phlegm-stasis occlusive perforator artery lesion,and to provide a new idea for clinical diagnosis and treatment of progressive cerebral infarction with phlegm-stasis occlusive perforator artery lesion.Methods:A total of 60 inpatients with progressive cerebral infarction of phlegm-stasis occlusive collateral artery lesion in the Department of Neurology,the Second Affiliated Hospital of Hunan University of Chinese Medicine were selected.All patients were divided into control group and experimental group by random number table method,with 30 cases in each group.During the study,one subject in the experimental group withdrew from the study due to changes in condition and one subject in the control group due to irregular medication.Finally,29 cases were completed in the experimental group and the control group respectively.The control group was given conventional Western medicine treatment,and the experimental group was treated with progressive stroke prescription on the basis of the control group for 14 days.The effects,NHISS,m RS Scores,TCM syndrome scores,D-D,LDL-C,hs-CRP,Hcy levels and the occurrence of adverse events were compared between the two groups after treatment.Results:After treatment,the neurological function efficacy,long-term efficacy and TCM efficacy of the experimental group were better than those of the control group(P < 0.05).NIHSS score,m RS Score and TCM syndrome score showed no significant difference between the two groups before treatment and when aggravated(P > 0.05).After 24 hours of treatment,the experimental group was significantly improved compared with the control group(P < 0.05).Compared with the levels of D-D,LDL-C,hs-CRP and Hcy in the two groups,all indexes were decreased after treatment,and the decrease in the experimental group was more obvious than that in the control group(P < 0.05).There were no adverse events during treatment in both groups.Conclusion:Apoplexy Progress prescription has definite clinical efficacy in the treatment of progressive cerebral infarction with phlegm-stasis blocking collateral perforator artery lesions,which can prevent neurological deterioration,reduce inflammation,reduce blood lipid,and improve limb dysfunction in post-stroke patients to a certain extent,and has advantages of better prognosis and less side effects.