High-resolution Magnetic Resonance Imaging Of The Brain Was Used To Observe The Calcification Characteristics Of Atherosclerosis In The Middle Cerebral Of Patients With Cerebral Infarction And The Analysis Of Related Factors

Objective:To study the correlation between the structural features,plaque composition,calcification degree and responsible plaque components of cerebrovascular wall under high-resolution magnetic resonance imaging in patients with acute cerebral infarction to understand the clinical factors related to different plaque features and their impact on short-term prognosis.Raise awareness of HRMRI and help more people identify possible risks early,so as to achieve early prevention and treatment of diseases in this population.Methods:1.This study was conducted by retrospectively analyzing 67 patients diagnosed with acute cerebral infarction who were hospitalized at the Second Hospital of Hebei Medical University from 2019.06 to 2022.06 and whose responsible vessel was shown to be the middle cerebral artery after performing cerebrovascular high-resolution magnetic resonance imaging.2.Observe case data and imaging data to calculate the proportion of calcification in different degrees of stenosis;3.To study patients in groups according to the nature of the plaque and the proportion of calcification in the plaque according to imaging data,and to further analyze the impact of the relationship between the amount of calcification in the plaque and the risk factors contributing to atherosclerosis on cerebral infarction and the short-term prognosis.Results : Example 67 responsibility was identified based on High resolution magnetic resonanc imaging(HRMRI).Patients with acute cerebral infarction whose artery is the middle cerebral artery,and the calcification was classified as mild or moderate according to the degree of calcification(no patients with severe calcification were found in this study),including 33 mild calcification patients,34 moderate calcification patients,different calcification degree patients risk factors are significantly different,1.hypertension,Age factors(>35 years),low-density lipoprotein(LDL)levels,and atherosclerotic plaque load are strongly associated with the development of moderate calcification within plaques:1).Patients aged >35 years and with hypertension for ≤ 5 years were more likely to develop mild calcification(P=0.045);2).≥35-year-old patients with grade 2 hypertension are prone to moderate calcification(P=0.002),and patients with grade 3 hypertension are prone to mild calcification(P=0.016);3).Patients with LDL ≤ 2.07mmol/L were prone to mild calcification(P=0.014),patients with LDL<≤ 2.97mmol/L 3.37mmol/L were prone to moderate calcification(P=0.037).4).>35-year-old patients with grade 2 hypertension have moderate calcification(P=0.002),and patients with grade 3 hypertension are prone to mild calcification(P=0.016);5).>35-yearold patients with serum LDL ≤ 2.07mmol/L are more likely to develop mild calcification(P=0.006);2.The difference between hyperhomocysteinemia,hyperuricemia and calcification degree is statistically significant,but it is not its risk factor;3.There was no obvious correlation between diabetes,smoking and drinking and the degree of calcification(P>0.05).Conclusions:1.There was significant variability in risk factors in patients with different degrees of calcification,with patients >35 years of age and the presence of hypertension being predisposed to calcification,and the degree of calcification correlating with years of hypertension and grading.2.LDL level is related to the degree of calcification,patients within normal LDL levels are prone to moderate calcification,and patients below normal levels are prone to mild calcification.3.The difference between hyperhomocysteinemia,hyperuricemia,and degree of calcification was statistically significant,but was not a separate risk factor.