Research On Sweat Glucose Detection System Based On OECT And NFC

Diabetes is a chronic metabolic disease,and long-term high blood sugar can cause serious complications in multiple organs of the human body.Diet,exercise,medication,and blood glucose monitoring are the mainstays of blood glucose management.Among them,blood glucose detection is an important part of blood glucose management for diabetic patients,but traditional blood detection requires puncture,which is not convenient for daily monitoring.Sweat contains blood-related physiological indicators to provide new ideas for non-invasive blood glucose monitoring.Therefore,the preparation of excellent sweat glucose sensors to achieve accurate detection of sweat glucose levels is of great significance in the more accurate and convenient blood glucose management of diabetic patients.In this paper,the research goal is to build a sweat glucose level detection system based on Organic Electrochemical Transistor(OECT)Electrode and Near Field Communication(NFC)Technology.Based on the preparation of sweat sensors based on OECT,combined with near field communication NFC technology,a sweat glucose detection system based on OECT electrodes and NFC technology is built.The artificial sweat sample solution was tested.In order to verify the feasibility of the detection system,this paper has done the following research work:First,according to the working principle of OECT to regulate the drain-source current Ids through the gate voltage V_g,the preparation of the OECT electrode and the functional modification of the gate were designed,and the feasibility of the OECT electrode for detecting artificial sweat samples was preliminarily verified.Afterwards,the OECT electrode was optimized and characterized,and the characterization results showed that the performance of the OECT electrode was optimized.The oxidation-reduction reaction of glucose on the enzyme-type OECT electrode generates a Faraday-induced current,which regulates the channel current of the transistor through the gate voltage.The detection of sweat glucose is realized according to the characteristic that the channel current is directly proportional to the sweat glucose level.Secondly,the NFC potentiostat module circuit composed of analog front-end,digital controller,programmable memory,voltage analog front-end&transimpedance amplifier is designed.The OECT electrode is connected to the interface of the module,and the potential between the energized potential gate and the drain-source is kept constant by controlling the polarization current output,and the gate voltage is adjusted to control the magnitude of the channel current,thereby realizing the detection of artificial sweat glucose.Finally,an artificial sweat glucose detection system was constructed by assembling the OECT electrode and the NFC potentiostat module.The detection system uses OECT electrodes to detect electrical signals,and records the detection results in real time through NFC communication.It has the characteristics of rapidity,non-invasiveness and low cost,and can realize convenient non-invasive blood glucose detection.This system provides an important theoretical and practical basis for the development and application of sweat glucose detection system based on OECT and NFC technology.