Application Of Early Warning Score Of Necrotizing Enterocolitis In Preterm Infants

ObjectiveTo study the efficacy of Neonatal Necrotizing Enterocolitis Early Detection Score(Neo NEEDS)in predicting the condition of premature infants by collecting and analyzing the clinical data of premature infants.The best cut-off value was obtained.To provide an objective basis for clinical medical workers to observe the condition of premature infants scientifically and effectively,and to lay the research foundation for the development of early warning score of necrotizing enterocolitis in premature infants in China.MethodsPremature infants who met the inclusion and exclusion criteria and were admitted to the Department of Neonatology of our hospital from January 1,2022 to December 31,2022 were selected as the study subjects.The data of Neo NEEDS and Modified neonatal early warning score(MNEWS)were collected within 2 hours after admission.A dynamic tracking table was used to record the scores of children every day during hospitalization.Neo NEEDS and MNEWS were scored according to the clinical data and vital signs monitoring values of the children.The receiver operatingcharacteristic(ROC)curve was drawn.According to the diagnostic accuracy and area underreceiver-operating curve(AUROC),the predictive efficacy of Neo NEEDS for the condition of preterm infants was obtained,which was the best cut-off value,sensitivity,specificity,positive predictive value and negative predictive value.The predictive efficacy of Neo NEEDS in preterm infants was compared with MNEWS score.Results1.The Neo NEEDS score of NEC group(4.66±1.23)was significantly higher than that of non-NEC group(2.72±1.03),and the difference was statistically significant(P<0.05).2.The optimal cut-off value of Neo NEEDS for predicting NEC in preterm infants was3.5,the AUROC was 0.91,and the corresponding sensitivity and specificity were 93.00% and81.00%,respectively.3.The best cut-off value of Neo NEEDS for predicting feeding intolerance(FI)in preterm infants was 2.5,the AUROC was 0.62,and the corresponding sensitivity and specificity were 68.90% and 58.00%,respectively.4.The best cut-off value of Neo NEEDS for predicting the death of preterm infants was4.5,the AUROC was 0.97,and the corresponding sensitivity and specificity were 83.30% and95.30%,respectively.5.The optimal cut-off value of MNEWS for predicting NEC in preterm infants was 7.5,the AUROC was 0.82,and the corresponding sensitivity and specificity were 53.30% and97.10%,respectively.Conclusion1.Neo NEEDS has a high predictive power for NEC or death in preterm infants.2.When Neo NEEDS score is 3.5,it can be considered to improve the nursing level of children and intervene in time to reduce the occurrence of disease deterioration.3.Neo NEEDS has poor predictive value for feeding intolerance in preterm infants.4.MNEWS is less effective than Neo NEEDS in predicting NEC in preterm infants.