Multi-stratified Visual Scoring Criteria And Pulmonary Occupational Lesions Correlation Analysis Of Prognosis

Objective Taking lung cancer with high mortality as a representative,this paper discusses the correlation between the pathological characteristics of malignant space occupying lesions and the uptake grade of imaging agents,whether there are differences in the uptake grade of imaging agents between different pathological types of lesions,and how to evaluate the optimal critical value of different pathological types of lesions according to the uptake grade,so as to improve the understanding of the metabolic characteristics of malignant lesions.Selecting appropriate organizations as reference backgrounds,a new and more detailed¹⁸F-FDG uptake level evaluation method with visual progression levels is constructed for the diagnosis and prognosis evaluation of malignant space occupying lesions,aiming to better stratify the lesions and provide decision-making basis for clinical practice.Methods 144patients with lung space occupying lesions diagnosed by CT and¹⁸F-FDG PET/CT examination in nuclear medicine Department of Affiliated Hospital of Inner Mongolia Medical University from January 2019 to December 2019 with pathological results were included as the study subjects.Group patients based on their gender,age,lesion diameter,smoking status,pathological characteristics,and other information to explore the correlation between the level of imaging agent uptake in lung occupying lesions and the aforementioned factors.SPSS26.0 was used for statistical analysis of data,percentage was used to describe counting data,（?）±s was used to describe the measurement data,S-W test and P-P chart were used to verify the distribution type of measurement data,measurement data subject to non normal distribution,Mann Whitney test and K-W test were used for inter group comparison,and rank correlation was used to analyze the correlation between indicators;Using COX regression for univariate and multivariate analysis of prognosis,to explore the independent influencing factors of lung space occupying lesions on OS;And draw K-M survival curves for multi-level visual scoring,histological grading,T staging,and TNM staging.The difference is statistically significant as P<0.05.Results In patients with lung space occupying lesions,the¹⁸F-FDG PET/CT showed a correlation between multi-stratified visual scoring criteria and various patient factors,including gender,smoking status,diameter,pathological type,histological grade,T stage,and TNM stage.The multistratified visual scoring was positively correlated with SUV_max.Furthermore,the multistratified visual scores of adenocarcinoma and carcinoma in situ were significantly lower than those of squamous cell carcinoma,while the scores for grade I lung space occupying lesions were significantly lower than those for grade III lesions.As the disease progressed and TNM stage increased,the multi-stratified visual score also increased significantly.Reference thresholds of 5～6 points and 6～7 points were appropriate to distinguish benign and malignant lesions and to predict histological grade of the lesions.Moreover,these factors reflected the prognosis of patients to some extent,and the multi-stratified visual scores could be used to evaluate patients’prognosis.Conclusion The implementation of multi-stratified visual scoring criteria improves the effectiveness of evaluating the uptake level of¹⁸F-FDG,enabling accurate predictions of pathological type,differentiation degree,and patient prognosis of lung space occupying lesions.Combining visual evaluation methods and semi-quantitative evaluation methods,along with standardization,enhances the role of PET/CT imaging in diagnosing and treating patients with malignant space-occupying lesions,decreasing reliance on invasive diagnostic methods.Reliable of malignant probabilities of space-occupying lesions proves valuable in clinical decision-making,providing better guidance and support for clinicians...