| Objective: :The rehospitalization rate of chronic heart failure remains high.On the basis of modern medical treatment,how to relieve symptoms,further reduce the recurrence rate and rehospitalization rate is the difficulty of current research.Professor Yu Zuoying proposed the correlation between the ’ triple energizer theory ’ and the essence of heart failure pathogenesis.The clinical study of Xinfukang granules based on this prescription in the treatment of chronic heart failure can lay a foundation for the development of new drugs.Methods:Will meet the chronic heart failure(qi deficiency and blood stasis type)of72 patients,they were randomly divided into two groups,one group was named as the treatment group(with western medicine basic treatment plus Xinfukang granules),another group was named as the control group(with western medicine basic treatment),after 4weeks for a course of treatment.The changes of LEE heart failure score,TCM syndrome score,cardiac function classification,6-minute walking test,NT-pro BNP value and Minnesota quality of life score were recorded before and after treatment in the two groups.The results of the treatment group(basic treatment with western medicine plus Xinfukang granule)and the control group(basic treatment with western medicine)were statistically analyzed.Results: 1.the treatment group and the control group of subjects before the experiment on the subjects of age,gender and duration of illness and other statistical analysis calculated p > 0.05,no significant difference,feasible.2.Changes in indicators after 1-4 weeks:(1)The TCM syndrome scores of the two groups were statistically analyzed before treatment p >0.05,which was comparable.After treatment,the scores of the two groups were improved compared with those before treatment,p < 0.05,which was statistically significant,and the treatment group was superior to the control group.(2)The total effective rate of the two groups was 94.5 % in the treatment group and 75 % in the control group.(3)Two groups of TCM single symptom score before treatment,the statistical analysis,no significant difference between the two groups of data comparable;after treatment,the data of the two groups were better than those before treatment,and the treatment group was better than the control group.(4)Lee ’s heart failure score was statistically analyzed.There was no significant difference between the two groups before treatment(p > 0.05).After statistical analysis of Lee ’s heart failure scores between the two groups and between the two groups,p< 0.05 was statistically significant,indicating that the treatment group was better than the control group.(5)Before treatment in the treatment group and control group on cardiac function classification after statistical analysis p > 0.05,no significant difference,comparable.After treatment,the total effective rate of the treatment group(88.8 %)was significantly higher than that(69.4 %),and after statistical analysis and comparison,p <0.05,with statistical significance.(6)Before treatment,the treatment group and the control group 6-minute walk test by statistical test showed p > 0.05,no significant difference,comparable.After treatment,the walking distance of the two groups was longer than that before treatment.The walking distance before and after treatment was statistically analyzed p < 0.05,and the treatment group was better than the control group.(7)Before treatment,the treatment group and the control group NT-pro BNP values were compared by statistical test showed p > 0.05,no significant difference,comparable.After treatment,the NT-pro BNP values of the two groups were lower than those before treatment.After statistical analysis before and after treatment,p < 0.05,and the treatment group was better than the control group.(8)Minnesota quality of life scale score,in the total score,physical strength,emotional these three points,the two groups before treatment by statistical analysis p > 0.05,no significant difference,comparable.After treatment,the scores of the three dimensions were improved compared with those before treatment.After statistical analysis,p < 0.05,with statistical difference,and the treatment group was better than the control group.Conclusion: 1.Based on the theory of triple energizer dialectical treatment of traditional Chinese medicine on the basis of conventional western medicine plus Xinfukang particles can better improve the clinical symptoms of chronic heart failure.2.Xinfukang granule can improve the quality of life of patients with CHF,reduce the economic and psychological burden.3.Xinfukang granule regimen can better control clinical risk factors.4.Based on the theory of triple energizer in conventional western medicine treatment on the basis of Xinfukang particles on the treatment of CHF clinical high efficiency,low risk,high practicality,worthy of further research and promotion. |
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