Discussion On Etiology Pathogenesis And Treatment Of Vascular Dementia Based On Correlation Theory Of Warm Disease And Damp Heat Disease

Objective:By collating the medical records and experiences of the four major scholars of the school of febrile diseases in treating dementia,we will recognize and develop the etiology,pathogenesis,and differentiation and treatment of vascular dementia using the theory of dampness and heat related to febrile diseases,with a view to better promoting the theoretical,clinical,and scientific research of vascular dementia.Methods:This article uses the "literature review method" to systematically comb the chapters and medical records related to damp-heat disease in the medical works of Ye Tianshi,Xue Shengbai,Wu Jutong,and Wang Mengying,screen out the discussions on the pathogenesis of damp-heat disease and dementia,explore the relationship between the two from the perspective of ancient medical books and modern mechanisms,and propose the thinking and methods of differentiation and treatment of damp-heat disease related theories in vascular dementia.Results:During the Ming and Qing Dynasties,the School of Febrile Diseases had a rich discussion on the etiology,pathogenesis,pathogenesis,treatment principles,methods,and medication characteristics of damp-heat disease.Among them,the understanding of damp-heat disease in the books and medical records of the four major scholars of febrile diseases provides a theoretical basis for the etiology,pathogenesis,and differentiation and treatment of vascular dementia in traditional Chinese medicine.The specific theoretical characteristics are summarized as follows: First,the theoretical characteristics of "turbid evil harms clearing" reflect the evolution rule of damp-heat turbid evil obscuring clearing the orifices,providing a theoretical basis for treating vascular dementia from the orifices.Secondly,the theoretical characteristics of "initial onset of dampness and heat in the meridians,and prolonged stagnation and heat entering the collaterals" and "prolonged and frequent occurrence of tsunamis will inevitably damage the collaterals" reflect the long-term stagnation of dampness and heat,and the disease enters the collaterals,causing brain collateral stasis or loss of nourishment,providing a theoretical basis for treating vascular dementia from the perspective of collaterals.3 、 The theoretical feature of "subject and object mixed reception" reflects the invasion of damp-heat pathogenic factors,which can consume human essence,blood,body fluid,diseases,and brain marrow in the later stage,providing a theoretical basis for treating vascular dementia from the perspective of marrow.Conclusion:1.Vascular dementia is treated from the "orifices"."Those who are harmed by turbid pathogenic factors are caused by dampness,heat,and turbid pathogenic factors.The main method for opening the orifices is to clear the orifices,and the main method is to open the orifices with fragrance.The aromatic method for removing turbid substances is to clear the orifices,remove the orifices,benefit the orifices,and clear the orifices.The selected recipe can be modeled on Wu Jutong’s three first-aid orifices,and the medicine contains Huoxiang,Baikoren,calamus,tulip,borneol,and musk.".The stomach is often responsible for the disease of orifices,and regulating the stomach to open the orifices is another great method.Those who suffer from damp-heat injury to the spleen and stomach,lack of biochemical sources of qi and blood,and lack of nourishment in the brain and orifices should be advised to invigorate the spleen and stomach to help transform the source;Damp heat affects the spleen and stomach,affecting the qi movement of the spleen and stomach.If the spleen does not rise and the turbid qi does not fall,it can be reversed.It is advisable to restore the qi movement of the spleen and stomach."For those whose dampness and heat turn into dryness,and whose pathogenic heat is abundant within,it may be considered to add or subtract Wendan Decoction;";"Heat accumulates in the body,causing deficiency in the internal organs,and is suitable for moistening the intestines and promoting circulation.With the aid of a moistening and drying agent,the method takes the meaning of Tongyou in Dongyuan."2.Treatment of vascular dementia is based on "collateral".The initial onset of dampness-heat disease is in the meridians,and after a long period of time,it enters the meridians to coagulate blood stasis,and the brain meridians are blocked.If the disease is deficient,the method should be used to replenish the essence and blood.It is advisable to cultivate and replenish the essence and blood with affectionate products of blood and flesh.If the essence and blood are prosperous,the channels of the meridians will be filled,and the blood vessels will be unblocked.In fact,the method of eliminating pathogenic factors and unblocking the collaterals is suitable.The medication can be treated in imitation of Wu Youke Sanjia Powder.In clinical practice,it can be treated with the similarities and differences of stagnant pathogenic factors,such as removing blood stasis and unblocking the collaterals,removing phlegm and unblocking the collaterals,clearing heat(fire)and unblocking the collaterals,or detoxifying and unblocking the collaterals,or both.3.Vascular dementia is treated from the "marrow"."If dampness and heat consume essence,blood,and body fluid,and damage the marrow,causing the marrow to decrease and the brain to dissipate,it is necessary to benefit the kidney and replenish the marrow.For those with yin deficiency,the method of nourishing yin and increasing fluid,filling the essence and replenishing the marrow,and nourishing and replenishing the deficiency can be imitated by Wu’s Jiajian Fumai Decoction.";"For those with deficiency of yang,the treatment is to warm yang and replenish qi,replenish deficiency and generate marrow.The method of warming yang and replenishing deficiency can be modeled on Xue’s" Fuyang Dehumidifying Decoction".With syndrome,attention should be paid to the transformation of deficiency and excess,with nourishing marrow and nourishing deficiency as the foundation,and eliminating pathogenic factors as the supplement.