Analysis Of The Effect Of Decompressive Craniectomy Combined With Intravascular Heat Exchange Technique In The Treatment Of Refractory Intracranial Hypertension

Objective: To observe the effect of intravascular heat exchange technique combined with decompressive craniectomy on the content of C-reactive protein and interleukin-6 in the treatment of Refractory intracranial hypertension.To investigate the effect of intravascular heat exchange technique combined with decompressive craniectomy on neurological recovery and prognosis of patients with Refractory intracranial hypertension.Methods: The clinical data of 44 patients with Refractory intracranial hypertension who underwent decompressive craniectomy in our hospital from March 2019 to June 2022-22 were retrospectively analyzed.According to whether they received endovascular cooling treatment,they were divided into observation group(18 cases)and control group(26cases).The IL-6 and CRP of the two groups were compared 3 days before and after operation.The GCS score and NIHSS score at 7 days before and after operation and the GOS score at 6 months after operation were compared.Results: 1.Inflammatory indicators: compared with the control group,the level of IL-6 in the observation group decreased after treatment,the difference was statistically significant(P < 0.05),and there was no statistically significant difference in C-reactive protein(P>0.05).(2)Degree of coma and neurological deficits: there were significant differences in GCS score and NIHSS score between the two groups before operation(P < 0.05).(3)The prognosis of the observation group was better than that of the control group,and the difference was statistically significant(P < 0.05).Conclusion: Endovascular heat exchange combined with decompressive craniectomy can effectively reduce Refractory intracranial hypertension.