Effects Of Sleep Quality On Propofol Dosage And Postoperative Sleep Quality In Painless Gastroenteroscopy Patients

Objective To investigate the effect of sleep disorders on the dosage of propofol in patients undergoing painless gastroenteroscopy and postoperative sleep qualityMethods eighty patients who received painless gastroenteroscopy in the painless center of our hospital from October 2021 to April 2022 were selected(a total of 116 cases were collected,36 of which were excluded for various reasons).Preoperative sleep quality and daytime sleepiness severity were assessed according to Pittsburgh Sleep Quality Index(PSQI)and Epworth Sleepiness Scale(ESS).Groups were divided according to whether there was sleep disorder before PSQI diagnosis.PSQI >7 was divided into sleep disorder group(n=40),PSQI≤7 was divided into normal sleep group(n=40).Sufentanil was slowly injected into the vein before induction in both groups 0.05-0.1 g/kg.Propofol was then slowly injected intravenously at a rate of 10mg/s.After the patient’s consciousness disappeared,no response to call,eyelash reflex disappeared,and alarm/sedation score(OAA/S)≤2,the intravenous injection of propofol was stopped and gastroenteroscopy was performed.Observe and record two groups of patients with dosage of propofol in the process of operation,preoperative and postoperative 24 hours and 7 d PSQI score and so on different time points and adverse reactions such as respiratory depression,body dynamic response is happening and the induction time,operation time,stomach and awakening time,check the end time to enter the recovery room.Results Main indicators: Compared with the normal sleep group,the initial dosage,total dosage and dosage per unit body surface per unit time of propofol in the sleep disorder group were significantly increased(P<0.05),and the PSQI scores of patients at 24 h and 7 days after surgery were decreased compared with those before surgery,the differences were statistically significant(P<0.05).Secondary indicators:Daytime sleepiness was associated with increased dosage of propofol.Compared with the normal sleep group,the waking time of the sleep disorder group was significantly longer than that of the normal sleep group(P<0.05).There was no significant difference between the two groups in the occurrence of intraoperative adverse events and the time of sending patients to the recovery room after examination(P>0.05).Conclusion Preoperative sleep disorder can increase the dosage of intravenous anesthetic propofol during painless gastroenteroscopy,and there will be delayed awakening phenomenon.The degree of daytime sleepiness of patients is related to the increase of the dosage of propofol,and the application of intravenous anesthetic can improve the sleep disorder of patients in a short term.