Objective:Through data mining technology,the core acupoint of acupuncture treatment for women’s perimenopausal insomnia is summarized,and the acupuncture point is combined with the transcranial repeated acupuncture therapy of Professor Sun Shentian,a master of traditional Chinese medicine,and then combined with jujube kernel decoction to treat cardiac and kidney perimenopausal insomnia.Method:1.Data mining: Literature on acupuncture treatment of perimenopausal insomnia was searched from electronic databases of China National Knowledge Network,VIP Journal and Wanfang Data Resource system,and the selected literature was input into Office Excel 2010 to form acupoint database.The frequency,frequency,specific acupoints,belonging meridians and distribution of human body parts were analyzed statistically.Cluster analysis was conducted on acupoints with frequency ≥5 times.SPSS Modeler 18.0software was used to analyze the association rules of acupoints.2.Clinical efficacy: A total of 32 patients meeting the inclusion criteria were included in this study,2 patients fell off during the study,and 30 patients were actually completed.The included patients were treated with transcranial repeated acupuncture combined with Suanzoren Decoction by self before and after control.The changes of FSH level,PSQI score,Kupperman score and TCM syndrome score before and after treatment were statistically analyzed.SPSS 21.0 software was used for processing and analysis to evaluate the clinical efficacy.Results:1.Data Mining:A total of 57 acupoints were involved,and the total frequency of use was371 times.15 acupoints were used more than 10 times,and the cumulative frequency of use was 253 times,accounting for 68.19% of the total frequency.Baihui,Sanyinjiao and Shenmen were the most frequently used acupoints.A total of 8 types of specific acupoints were involved,and the most frequently used specific acupoints were Yuan acupoints,followed by five acupoints,Back Shu acupoints,mu acupoints,eight mai intersection acupoints,Bahui acupoints,Luo acupoints and Xiaxhe acupoints.In common meridians,points on Ren pulse,foot sun bladder meridian and Du pulse were selected,and the total frequency was 164 times,accounting for 44.20%.The most commonly used acupoints were distributed in lower limbs,head,neck,chest and abdomen,with a total frequency of 267 times,accounting for 71.97%.Association rule analysis: 15 association rules with support degree greater than 0.3 and confidence degree greater than 0.8 were symbiosis.It was found that Guanyuan-Shenmen-Sanyinjiao and Qihai-Guanyuan had strong association,and Guanyuan,Shenmen,Sanyinjiao,Qihai,Taixi and Baihui were the core acupoints for treating perimenopausal insomnia.Three cluster groups,cluster 1: Shenshu,Xinshu,Ganshu,Shenting,Benshen,Hegu;Cluster 2 categories: Baihui,Neiguan,Sanyinjiao,Shenmen,Tianshu,uterus,Zhongwan,Xiawan,Guanyuan,Qi Hai,Zusanli,Yintang;Cluster 3 categories:zhaohai,Shenmai,Taixi,Taichong,sishencong,anmian.2.Clinical efficacy:FSH level,PSQI score,Kupperman score and TCM syndrome score were decreased after treatment,and the difference was statistically significant(P<0.001).The total effective rate of TCM syndrome was 96.67%,and the total effective rate of comprehensive curative effect was 93.33%.Conclusion:1.In terms of acupoint selection in the treatment of perimenopausal insomnia,The frequency of use of Baihui,Sanyinjiao and Shenmen acupoints was the highest;Among the specific acupoints,the original acupoints,the five acupoints and the Back Shu acupoints were the most frequently used;In the distribution of human body parts,more lower limbs,head,neck,chest and abdomen acupoints;In the meridians,take more Ren pulse,foot sun bladder meridian,Du pulse points;In the association rules,it was found that Guanyuan-Shenmen-Sanyinjiao,Qihai-Guanyuan and other points have a strong association,which are commonly used in the treatment of perimenopausal insomnia,and Guanyuan,Shenmen,Sanyinjiao,Qihai,Taixi,Baihui and other points belong to the core acupuncture points for the treatment of perimenopausal insomnia.2.In the treatment of perimenopausal insomnia of heart-kidney dissonant type,repeated transcranial acupuncture combined with Suanzoren decoction can prolong the patients’ sleep time,improve the sleep quality and reduce their TCM syndromes.No adverse reactions were found during the study,which can be applied to clinical practice. |