Study On The Correlation Between TBIL,non-HDL-C And Different Traditional Chinese Medicine Syndromes Of Stable Angina Pectoris In Patients With Coronary Heart Disease

Objective:By studying the correlation between TBIL,non-HDL-C and traditional Chinese medicine syndrome types of stable angina pectoris in coronary heart disease,this study provides a certain reference for the differentiation of stable angina pectoris in coronary heart disease in traditional Chinese medicine.Method:162 patients with stable angina pectoris and 30 healthy individuals were selected from the Cardiovascular Department of the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from December2021 to December 2022.Through the four diagnostic methods of traditional Chinese medicine,patients with stable angina pectoris were classified according to traditional Chinese medicine(TCM)syndrome differentiation.Basic information and TBIL,DBIL,IBIL,TC,HDL-C,non-HDL-C values were observed and recorded.SPSS 26.0 was used for analysis to study the correlation between TBIL,non-HDL-C,and TCM syndrome types of stable angina pectoris in coronary heart disease.Results:1.Compared with the healthy control group,the levels of TBIL,DBIL,and IBIL in each TCM syndrome group of SAP patients decreased with statistical significance(P<0.05),while the levels of TC and non-HDL-C increased with statistical significance(P<0.05).2.The distribution of traditional Chinese medicine syndrome types in SAP patients is as follows: 40 cases(24.7%)in the Qi deficiency and blood stasis syndrome group,39 cases(24.1%)in the phlegm turbidity blockage syndrome group,30 cases(18.5%)in the Qi stagnation and blood stasis syndrome group,20 cases(12.3%)in the heart blood stasis syndrome group,15 cases(9.3%)in the Qi yin deficiency syndrome group,15 cases(9.3%)in the heart kidney yang deficiency syndrome group,2 cases(1.2%)in the heart kidney yin deficiency syndrome group,and 1 case(0.6%)in the cold coagulation heart meridian syndrome group.3.The average age of various traditional Chinese medicine syndrome types in SAP patients,from high to low,is as follows: Qi and Yin deficiency syndrome,Qi deficiency and blood stasis syndrome,Heart kidney yang deficiency syndrome,Heart blood stasis syndrome,Phlegm turbidity blockage syndrome,Qi stagnation and blood stasis syndrome,with statistically significant differences(P<0.05).4.The gender distribution of various traditional Chinese medicine syndrome types in SAP patients was not statistically significant(P>0.05).5.The levels of TBIL and IBIL in SAP patients with various traditional Chinese medicine syndrome types,from high to low,are as follows: Qi stagnation and blood stasis syndrome,heart kidney yang deficiency syndrome,Qi yin deficiency syndrome,heart blood stasis syndrome,Qi deficiency and blood stasis syndrome,and phlegm turbidity blockage syndrome,with statistically significant differences(P<0.05).The order of DBIL levels from high to low is: Qi stagnation and blood stasis syndrome,heart blood stasis syndrome,Qi deficiency and blood stasis syndrome,Qi yin deficiency syndrome,heart kidney yang deficiency syndrome,and phlegm turbidity blockage syndrome,with statistically significant differences(P<0.05).6.The TC levels of various traditional Chinese medicine syndrome types in SAP patients,from high to low,are as follows: phlegm stagnation syndrome,heart blood stasis syndrome,qi yin deficiency syndrome,qi deficiency and blood stasis syndrome,heart kidney yang deficiency syndrome,and qi stagnation and blood stasis syndrome,with statistically significant differences(P<0.05).7.The levels of non-HDL-C in SAP patients with various traditional Chinese medicine syndrome types,from high to low,are as follows: phlegm turbidity blockage syndrome,heart blood stasis syndrome,qi deficiency and blood stasis syndrome,qi yin deficiency syndrome,heart kidney yang deficiency syndrome,and qi stagnation and blood stasis syndrome,with statistically significant differences(P<0.05).8.The correlation analysis results show that the syndrome of qi stagnation and blood stasis is positively correlated with TBIL levels,the syndrome of phlegm stagnation and obstruction is negatively correlated with TBIL levels,and is positively correlated with non-HDL-C levels.9.The ROC curve analysis results show that in patients with Qi stagnation and blood stasis syndrome,the area under the TBIL indicator curve is 0.811,and the sensitivity of the maximum diagnostic index is 76.7%,with a specificity of 82.2%.In patients with phlegm turbidity obstruction syndrome,the area under the non-HDL-C index curve is 0.714,with a sensitivity of 59.0% and a specificity of 77.5% for the maximum diagnostic index.Conclusion:1.In this study,compared with the healthy control group,SAP patients had lower serum TBIL levels and higher non-HDL-C levels.2.In this study,there were differences in TBIL,DBIL,IBIL,TC,and non-HDL-C among traditional Chinese medicine syndrome types in SAP.3.In this study,TBIL levels have a predictive effect on SAP Qi stagnation and blood stasis syndrome.4.In this study,the level of non-HDL-C has a predictive effect on SAP phlegm stagnation syndrome.5.In this study,the levels of TBIL,DBIL,IBIL were negatively correlated with TC and non-HDL-C.