Clinical Application Of Sublingual Veins Diagnosis In Ischemic Stroke

Objective: By observing the sublingual veins in patients with ischemic stroke(IS)and analyzing the correlation between the abnormal changes and the level of cerebral artery atherosclerotic stenosis(CAAS),plasma D-dimer(D-D)and fibrinogen(FIB)as well as the degree of neurological impairment,the clinical application value of sublingual veins diagnosis in IS was discussed.Methods: From March 2022 to March 2023,IS patients(IS group)and non-IS patients(non-IS group)hospitalized in the Department of Encephalopathy of Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region were collected.The related examinations and scores were completed in both groups,and the general data of the patients(age,gender,BMI,etc.)were collected,past medical history(hypertension,diabetes,coronary heart disease,,etc.),imaging data(head MRI/CT report,head and carotid CTA report),coagulation function report(D-D and FIB measurement),NHISS score of IS patients,the correlation between the abnormal changes of sublingual veins and the levels of CAAS,D-D and FIB in the two groups,and the correlation between the changes of sublingual veins and the degree of neurological impairment in the IS group were analyzed and compared.Results: 1.Data collation and statistical analysis were conducted on the relevant data of the two groups,indicating that the sublingual veins in the IS group accounted for 93.75%,and the syndrome of blood stasis syndrome accounted for 61.46%.The average score of sublingual veins was 10.7higher than that in the non-IS group,and the difference of blood stasis syndrome was statistically significant(P<0.05).2.The comparison of signs of sublingual veins suggested that the changes of wide diameter and extraneous comorbidity in the IS group were more serious than those in the non-IS group.Compared with the general data and past medical history,the number of males,smoking,hypertension,diabetes and coronary heart disease in the IS group was more common than that in the non-IS group,and the differences were statistically significant(P<0.05).The degree and number of CAAS in the two groups were compared,and the degree of CAAS and the number of two or more strictures in the IS group were higher than those in the non-IS group,with statistical significance(P<0.05).There was no significant difference in the level of D-D and FIB(P>0.05).The sublingual veins change and the degree of neurological impairment in the 96 patients in the IS group were tested by pearson correlation test(P>0.05),indicating no correlation.3.The correlation test was conducted between the score and grade of the sublingual veins of 190 patients who completed head and carotid artery CTA and the degree and number of CAAS,and the correlation coefficient r < 0.2 suggested no significant correlation.4.The 90 patients with abnormal sublingual veins in the IS group were statistically described,and the most common TCM syndrome elements were phlegm 63 times(31.5%);Among the stages of apoplexy,wind was the most common 36 times(58.06%)in the acute stage,phlegm was the most common 19 times(30.16%)in the convalescence stage,and blood stasis syndrome was the most common 15 times(30%)in the sequelae stage.Conclusion:1.Abnormal sublingual veins and blood stasis syndrome are common in IS patients.The changes of sublingual veins are related to gender,smoking,hypertension,diabetes,coronary heart disease and other factors.2.The more severe the changes of sublingual veins,the more number and severity of CAAS.3.The most common TCM syndrome element in stroke patients with abnormal sublingual veins is phlegm;Among the TCM syndromes in each stage of stroke,wind is the most common in the acute stage,phlegm is the most common in the recovery stage,and blood stasis is the most common in the sequelae stage.