Histological And Bone Mineral Density Analyses Of The Mandibular Lamellar/Oblique Fracture Healing In Beagles

Objective:The goal of this study was to determine whether there were any differences in the healing processes for linear fractures and lamellar/oblique mandibular fractures.Method:Using a random number generator,two groups of six beagle dogs each were created from a group of twelve.The experimental group was the lamellar/oblique fracture of the mandible,while the control group was the traditional linear fracture of the mandible.The first premolar and the first molar were where the fracture occurred.Two 4-hole bone plates were used to repair the fracture line.After two weeks,one month,and three months,we examined the samples.Results:X-ray:the experimental group’s fracture space was fuzzier and eventually disappeared between the two groups.Histology:the Collagen Volume Fraction in the experimental group was lower than that in the control group three months after surgery(0.114±0.090VS0.429±0.006,P<0.05).The experimental group had more bone cells than the control group did one month following the surgery(108.0±1.4VS88.0±2.8,P<0.05).Both groups’ trabecular arrangements became more regular as the healing process progressed.BMD:the experimental group’s BMD was higher than the control group’s one month following surgery(0.765±0.076VS0.142±0.024,P<0.05).Laser confocal microscopy:The average fluorescence intensity of the experimental group was higher than that of the control group at 2 weeks and 3 months after operation.(36.20±0.49 VS 26.20±2.75)(P<0.05);(41.67±6.36 VS 12.97±2.22)(P<0.05).Other times,it was impossible to distinguish between the two groups.Concousion:In comparison to traditional linear fractures,lamellar/oblique fractures of the mandible have higher bone mineral densityand heal more quickly.