Analysis Of Prognostic Factors Of Thoracolumbar Vertebral Osteoporotic Fracture

Objective With the aging of the population,the bone mass of the elderly is declining,and the number of osteoporosis patients is increasing.The incidence rate of osteoporotic fractures is also increasing.Osteoporotic fractures can occur in the bones of the limbs and spine.In addition to hip fractures,vertebral compression fractures account for the vast majority of them.This kind of patients can only occur due to slight external force.The patients have severe pain in their back and waist,which can be relieved after absolute bed rest.Some patients have lost their ability of daily living in the long term,which seriously reduces their quality of life.It is found that the prognosis of fracture patients is different due to some factors.In this paper,we retrospectively analyzed the relevant representative factors that affect the good prognosis of such patients,studied the relevant factors that affect the prognosis of thoracolumbar vertebral osteoporotic fracture,and actively intervened with clear risk factors,which can avoid or reduce the occurrence of bad prognosis to a certain extent.Method This study retrospectively analyzed the patients with osteoporotic vertebral fracture who visited our hospital from January 2020 to October 2021.Through screening,a total of 313 patients were included in the study.According to the hospitalization information,record the age,sex,body mass index,bone density,MRI type of injured vertebra,whether there is single vertebral fracture,whether there is surgical treatment,whether there is central and posterior column involvement,whether there is a history of diabetes in the past,whether there is regular anti osteoporosis treatment,and evaluate the prognosis of patients with Barthel index 12 months after discharge.According to Barthel index,a score above 60 points is classified as a good prognosis group,and a score below 60 points is classified as a bad prognosis group.To study the influencing factors of thoracolumbar vertebral osteoporotic vertebral compression fracture,SPSS 22.0 statistical software was used for analysis.The measurement data were expressed as mean ± standard deviation,the counting data were used for chi-square test,and the non-conditional logistic regression model was used to analyze the relevant factors affecting fracture prognosis.Results Of the 313 cases,279 had a good prognosis(good prognosis group)and 34 had a bad prognosis(bad prognosis group).The results of univariate analysis of the two groups showed that age(=0.377,P=0.770),sex(=0.235,P=0.628),bone mineral density(=1.448,P=0.230),whether single vertebral fracture(=1.243,P=0.266),whether surgical treatment(=0.082,P=0.775)There was no significant difference in whether the middle and posterior columns were involved(=1.412,P=0.236)and whether there was a history of diabetes(=1.347,P=0.247);There were significant differences in body mass index(=18.611,P=0.000),MRI type of injured vertebra(=96.399,P=0.000)and whether anti-osteoporosis treatment was regular(=341.028,P=0.000).The results of multiple logistic regression analysis showed that high BMI(OR=0.067,P=0.006),diffuse low signal(OR=0.076,P=0.021)and irregular anti-osteoporosis treatment(OR=128.262,P=0.000)were independent risk factors for poor prognosis of osteoporotic vertebral compression fracture.Conclusion Spine is the most common part of osteoporotic fracture due to its special physiological bone structure and stress.The patients with osteoporotic vertebral compression fracture suffered more pressure on their spine when their body mass index was high,which affected the fracture prognosis;When the MRI of the injured vertebra showed diffuse low signal,the edema in the injured vertebra was serious,and the damaged vertebra was extensive,which affected the prognosis of the fracture;Failure to carry out regular anti-osteoporosis treatment is not conducive to bone regeneration and affects fracture prognosis.