Risk Factors Analysis Of Premature Death From Noncommunicable Diseases Among Employees In X System

Aim: Noncommunicable diseases related premature death of adults is an urgent problem threatening the health of human beings and demanding prompt solution.This study explored the risk factors of noncommunicable diseases related premature death among employees in the Hunan X system,to provide the basis for clinical intervention.Methods: We collected premature death cases from Hunan X system from March 2017 to June 2020.And we screened the causes of death and included only employees for noncommunicable diseases related premature death.By conducting health questionnaires and physical examination reports,we collected relevant health care data,such as blood test,abdominal ultrasound scan and other information,and personal living behavior data,such as previous disease history,work/living habits,characteristics and other information.These cases were divided into sudden death case group and non-sudden death case group according to the time of death.On this basis,a case-control study was conducted,with age and gender matched normal controls(1:2 ratio)that were divided into sudden death control group and non-sudden death control group.Then we analyzed the risk factors related to sudden death and non-sudden death cases.Results: There were 81 premature death cases from noncommunicable diseases,including 39 cases of sudden death and 42 cases of non-sudden death.Among sudden death group,there were 21 cardiac sudden death cases,14 brain sudden death cases,and 4 sudden death cases of unknown cause.Among non-sudden death group,there were 34 deaths from malignant tumors,3 deaths from liver cirrhosis complications,2 deaths from diabetes complications,and 1 death respectively from chronic renal failure,chronic heart disease,and cerebrovascular disease.Risk factor analysis of sudden death cases group: One: The results of univariate analysis showed that,compared with the sudden death control group,blood indexes in sudden death case group such as white blood cell,lymphocyte,neutrophil,monocyte,platelet distribution width,serum creatinine and total cholesterol level were higher,while hemoglobin,platelet lymphocyte ratio,mean hemoglobin and mean platelet volume level were lower.Besides,body mass index,systolic blood pressure,resting heart rate,fatty liver rate,sociability score and no exercise habit ratio in the sudden death case group were higher,while educational level were lower.Two: Multivariate logistic analysis showed that resting heart rate,total cholesterol level and exercise habits were independently associated with the risk of sudden death(P<0.05).Risk factor analysis of non-sudden death cases group: One: The results of univariate analysis showed that,compared with the non-sudden death control group,blood indexes in non-sudden death case group such as red blood cells,hemoglobin,platelets,hematocrit,lymphocyte monocyte ratio,mean platelet volume and low density lipoprotein(LDL)level were lower,while neutrophil lymphocyte ratio(NLR),monocytes,red cell distribution width,aspertate aminotransferase,and globulin level were higher.Besides,exercise habit,total exercise time and educational level were lower in the non-sudden death case group,while field work types in the non-sudden death case group were higher.Two: Multivariate logistic analysis showed that LDL level,NLR,monocytes,educational level and exercise habits were independently associated with non-sudden death(P<0.05).Conclusions: In the sudden death group,cardiovascular and cerebrovascular diseases were the leading causes of death.And increased resting heart rate,high total cholesterol level and lack of exercise habits are independent risk factors for sudden death.In the non-sudden death case group,malignant tumor were the leading causes of death.And high NLR,monocytes,low LDL,low educational level and no exercise habits were independent risk factors for non-sudden death.1 picture,24 tables,127 references...