Clinical Study Of CT-guided Radiofrequency Thermocoagulation Of Thoracic Sympathetic Nerve For Chest Pain After PCI

Objective:To explore the clinical efficacy and safety of radiofrequency thermocoagulation of thoracic sympathetic nerve in the treatment of chest pain after PCI,and provide more effective methods and references for the treatment of chest pain after PCI.Methods:In this study,a retrospective cohort study was conducted to retrospectively analyze the cases of patients with chest pain after PCI who were treated in China-Japan Union Hospital of Jilin University from November 2020 to June 2022.The 66 patients who met the inclusion criteria were divided into control group(30 cases)treated with oral nonsteroidal analgesic drugs and radiofrequency group(36 cases)treated with radiofrequency thermocoagulation of thoracic sympathetic nerve.General data,including age,gender composition and course of disease,were analyzed and compared between control group and radiofrequency group.VAS scores of chest pain in control group and radiofrequency group were analyzed and compared before treatment and after 1 day,1week,1 month and 3 months.The frequency of weekly chest pain episodes and the duration of each chest pain were compared between control and radiofrequency groups before and 3 months after treatment.The improvement of concomitant symptoms after 3 months was compared between control group and radiofrequency group.The clinical efficacy of control group and radiofrequency group were evaluated and compared 3 months later.Adverse reactions were recorded in control and radiofrequency groups,and their incidence was compared.Results:1.There was no difference in general data between the control group and the radiofrequency group before treatment.2.Compared with before treatment,the VAS score of chest pain in the control group and radiofrequency group decreased after 1 day,1 week,1 month and 3 months of treatment,and the reduction in radiofrequency group was more significant than that in the control group(P<0.05).3.The frequency of chest pain attack per week in the control group and the radiofrequency group after treatment was lower than that before treatment,and the decrease was more significant in the radiofrequency group(P<0.05).4.The duration of chest pain in the control group and radiofrequency group after treatment was lower than that before treatment,and the reduction was more significant in radiofrequency group(P<0.05).5.After 3 months of treatment,the clinical efficacy of patients in the radiofrequency group was better than that in the control group(P<0.05).6.After 3 months of treatment,the improvement of concomitant symptoms of patients in the radiofrequency group was higher than that in the control group(P<0.05).7.There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:1.Compared with oral non-steroidal analgesics,CT-guided radiofrequency thermocoagulation thoracic sympathetic nerve has better effect than oral non-steroidal analgesics in the treatment of chest pain after PCI.2.CT-guided radiofrequency thermocoagulation thoracic sympathetic technology has high safety and no serious complications.3.CT-guided radiofrequency thermocoagulation of thoracic sympathetic nerve is a new minimally invasive method for the treatment of chest pain after PCI,which is worthy of popularization and research.