Intravascular Interventional Treatment Of Acute Non-arteritic Central Retinal Artery Occlusion

Objective:To investigate the effectiveness of intravascular intervention in the treatment of acute non-arteritic central retinal artery occlusion.Methods:This is a retrospective study based on data obtained from the Stroke Center of the First Hospital of Jilin University.We collected data from all patients with central retinal artery occlusion who underwent endovascular intervention treatment from October 2020 to February 2023,screened 13 patients who met the screening criteria,and collected relevant clinical and imaging data.Results:Each patient had at least one vascular risk factor.The most common vascular risk factor was hyperlipidemia(53.8%),followed by smoking(46.2%),hyperhomocysteinemia(46.2%),hypertension(30.8%),alcohol consumption(23.1%),cerebral infarction(23.1%),diabetes(15.4%),arrhythmia(15.4%)and family history of vascular disease(7.7%).A total of 9 cases(69.2%)had improved visual acuity,of which 2 cases(15.4%)had significantly improved visual acuity(both improved to0.6),7 cases(53.8%)had slightly improved visual acuity,and 4 cases(30.8%)had no significant change.Of the 13 patients,7 were accompanied by severe stenosis or occlusion of the affected carotid artery,and 3 underwent revascularization surgery(2patients had significantly improved vision,1 patient had slightly improved vision).Four patients with CRAO underwent intravascular interventional therapy within 6hours(3 with recanalization of the internal carotid artery,1 with simple thrombolysis),of which 3 had improved visual acuity(2 had significantly improved visual acuity,1had slightly improved visual acuity),and 1 had no change in visual acuity.There was no significant improvement in visual acuity in patients who underwent intravascular interventional therapy(9 cases of arterial thrombolysis)for more than 6 hours.There were no serious complications such as fundus hemorrhage,symptomatic intracranial hemorrhage,and ischemic stroke in all patients.Conclusion:Intravascular intervention is feasible for the treatment of acute non-arteritic central retinal artery occlusion caused by internal carotid artery occlusion;The time of interventional surgery is an important factor affecting the prognosis of patients;Emergency CRAO reperfusion therapy should be added to the green channel of emergency stroke treatment to improve the outcome of emergency treatment.