Objective:To investigate the efficacy and safety of percutaneous coronary intervention(PCI)via radial artery route in the treatment of elderly patients with coronary artery disease(CHD),and to analyze the effect of coronary intervention in patients with coronary artery disease combined with left heart insufficiency,related complications and the impact on the prognosis of implanted patients,in order to provide some reference on the medication and health management of patients after coronary stenting.Methods:To review the clinical outcomes of 240 patients with advanced coronary artery disease admitted to our hospital from October 2016 to May 2019 who underwent PCI with different puncture routes in the view.To review the general condition,relevant medical history,clinical outcome,pre-hospital and in-hospital treatment,post-discharge general condition and medication,and cardiovascular adverse events of patients who came to our hospital for coronary artery disease combined with left heart insufficiency with coronary angiography and drug eluting stent(DES)implantation from January 2016 to January 2021,and other clinical The data were statistically analyzed around the relevant observation indexes.Results:(1)There was no statistically significant difference between the radial artery group and the femoral artery in terms of procedure success rate,procedure time,X-ray exposure time,postoperative bed rest time and contrast dosage(P > 0.05),However,the length of postoperative bed stay and the incidence of complications were significantly different between the two groups(P < 0.05).(2)The cardiac function indexes such as low voltage differential signalling(LVDs),left ventricular end diastolic dimension(LVDd)and left ventricular ejection fraction(LVEF)in the observation group were significantly better than those in the reference group(P < 0.05);the New York Heart Association(NYHA)classification and 6-minute walk test(6MWT)in the observation group were significantly greater than those in the reference group(P < 0.05);the quality-of-life score(SF-36)was significantly higher than that of the reference group(P < 0.05).(3)Among the 277 patients who completed follow-up in the observation group,27 patients had MACE events,accounting for 9.75%,and 10 patients with all-cause cardiovascular death,accounting for 37.04% of patients with MACE events and3.61% of all patients followed up.There were 7 patients with gastrointestinal bleeding,accounting for 2.53%.(4)After coronary intervention with DES implantation,the occurrence of MACE events was strongly associated with age,out-of-hospital compliance with regular medication,preoperative LVEF,number of implanted DES,and preoperative cardiac function rating(P<0.05).(5)Age and preoperative LVEF are one of the risk factors for inducing gastrointestinal bleeding.Conclusion:(1)Coronary interventions performed via the radial route in advanced coronary artery disease are safe and feasible,with fewer complications。(2)Percutaneous coronary intervention treatment of coronary heart disease combined with left heart insufficiency can quickly and effectively promote the recovery of left heart function,improve the prognosis,and help to improve the overall living standard of patients,which can be used in clinical practice.(3)Age,whether to use drugs according to the doctor’s order outside the hospital,preoperative LVEF,and the number of DES implanted are independent risk factors for inducing postoperative MACE events.The preoperative LVEF is an independent risk factor for gastrointestinal hemorrhage. |