ObjectiveTo observe the curative effect of percutaneous liver puncture and drainage combined with hepatic artery catheterization and antibiotic injection in the treatment of bacterial hepatic abscess.MethodsNinety-eight eligible patients with bacterial liver abscess admitted to Ruijin People’s Hospital from April 2020 to May 2022 were selected for the study.Patients admitted from April 2020 to April 2021 were included in the control group(n = 47),and patients admitted from May 2021 to May 2022 were included in the observation group(n = 51).The control group received percutaneous liver puncture catheter drainage combined with peripheral venous pump antibiotic treatment,and the observation group received percutaneous liver puncture catheter drainage combined with hepatic artery catheter pump antibiotic treatment.General baseline data of patients in both groups were recorded before surgery,and the postoperative recovery time of patients’ physical signs,the changes of inflammatory indicators,liver function indicators and the occurrence of complications were observed at 1,3 and 7 days after surgery.Results(1)The time of body temperature returning to normal,the time of white blood cells returning to normal,the time of clinical symptom disappearance and the time of hospitalization in the observation group were shorter than those in the control group(P<0.05).(2)CRP,PCT,IL-6,TNF on the first day,the third day and the seventh day after operation in the observation group-α The changes of inflammatory factors were lower than those in the control group(P<0.05).(3)The levels of AST,TB,ALT and GGT in the observation group on the first day,the third day and the seventh day after operation were lower than those in the control group(P<0.05).(4)The complication rate in the observation group was 3.92%,which was lower than that in the control group(17.02%,P<0.05).(5)The total effective rate of the observation group was 98.04% higher than that of the control group(82.98%,P<0.05).ConclusionThe curative effect of percutaneous liver puncture drainage combined with hepatic artery catheterization pump antibiotics in the treatment of bacterial hepatic abscess is superior to that of percutaneous liver puncture drainage combined with peripheral venous pump antibiotics.Percutaneous liver puncture drainage combined with hepatic artery catheterization pump antibiotics can be the first choice for the treatment of bacterial hepatic abscess. |