| Objective:Two-dimensional shear wave elastography(2D-SWE)was applied to evaluate the changes in liver tissue stiffness before and after transhepatic arterial chemoembolization(TACE)for hepatocellular carcinoma,and to explore its clinical application in assessing the effects of TACE treatment on liver reserve function.Methods:Thirty-nine patients with primary liver cancer who underwent TACE in Ganzhou People,s Hospital from October 2021 to December 2022 were selected according to the enrollment criteria.All patients underwent abdominal ultrasound examination and liver 2D-SWE examination in addition to various routine examinations one week before surgery,one month after the first TACE,one month after the second TACE and one month after the third TACE.Child-Pugh was scored according to the examination results,and was divided into three levels according to the scores.The changes of 2D-SWE examination,serum liver function indexes and Child-Pugh grading in different time periods before and after surgery,as well as the correlation between them,were analyzed.Results:1.The liver function indexes after the third TACE treatment were significantly different from those before surgery(p < 0.05);2.The LS values in different times of one month after TACE were significantly different from those before TACE(p <0.05),and the serum liver function indexes before TACE were positively correlated with LS values;3.Before TACE and after different times of TACE,LS values increased with increasing Child-Pugh grade,and the differences in LS values between the Child-Pugh A and Child-Pugh(B+C)groups were statistically significant(p <0.05).Besides,the LS value before and after TACE was positively correlated with Child-Pugh grade.Conclusion:The 2D-SWE technique allows non-invasive,real-time and quantitative assessment of changes in liver elasticity values after TACE in patients with liver cancer,providing a valuable non-invasive imaging method for clinical evaluation of liver reserve function. |
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