| Purpose: Through the analysis of 281 cases of Osteoporotic Vertebral Compression Fracture(OVCF)treated by Percutaneous Vertebroplasty(PVP)in the Department of Spine Surgery of the Affiliated Hospital of Yan’an University during 3 years from 2019.9to 2022.9,we summarized the clinical characteristics of this disease and analyzed the efficacy of post-PVP.A case study of OVCF was conducted to summarize the clinical features of the disease,analyze the efficacy of PVP,and understand the complications associated with cement leakage and re-fracture,in order to further help the diagnosis and treatment of the disease.Methods: A total of 281 patients who met the inclusion criteria for OVCF were selected for the case search.Gender,age,occupation,Body Mass Index(BMI),cause of injury,fracture type,fracture segment,preoperative and postoperative VAS scores,ODI index,height of the anterior border of the injured vertebra and Cobb angle,Bone Cement Leakage(BCL)and fractured vertebrae were collected and analysed using SPSS27.0software.The analysis was performed using SPSS27.0 software.RESULTS: All 281 OVCF patients with a total of 341 vertebrae were successfully discharged after PVP surgery.The age distribution of the patients ranged from 51 to 91 years with a mean age of 71.57 ± 9.48 years,with a mean age of 72.32 ± 11.32 years for men and 71.35 ± 8.87 years for women.The highest percentage,32.03%,was in the60-69 age group.There were 65 males(23.13%)and 216 females(76.87%).The prevalence was significantly higher in women than in men,with no statistically significant difference between the two ages(p>0.05).68.33% of the patients had a BMI within the normal range,and the place of residence of the patients attending the clinic was mainly rural(61.21%),with more farmers(58.01%)than workers and clerical staff.The highest proportion of fractures occurred in the thoracolumbar segment(T11-L2)(57.18%).The highest number of single vertebral fractures occurred in 80.43% of cases.The main cause of injury for patients was a fall(45.55%).Type IIA was the predominant fracture type,accounting for 58.65% of the fractures.The VAS score and ODI index were significantly lower,the height of the anterior border of the injured spine was higher and the Cobb angle of the injured spine was smaller at 3 days and 6 months postoperatively compared to preoperatively,all of which were statistically different(p < 0.05).No significant changes were found in any of the four indices at 6 months postoperatively compared to 3 days postoperatively,with no statistical difference(P > 0.05).The postoperative CT scan revealed BCL in 194 vertebrae,with a leakage rate of 56.89%,and the frontal and lateral X-ray showed BCL in 98 vertebrae,with a leakage rate of 28.74%.The sensitivity of the X-ray film observation of BCL was 50.52% and the specificity was100%,using CT as the standard.).CT examination revealed differences in intravascular leakage,intracanalicular leakage and mixed leakage compared to X-ray(P < 0.05).During postoperative follow-up,23 patients had vertebral re-fractures,with an incidence of 8.19%,of which 14(4.98%)were adjacent vertebral re-fractures and 9(3.20%)were non-adjacent vertebral fractures.86.96% of the re-fractures were in women,and there was no statistical difference in the incidence of re-fractures in male and female patients(P > 0.05).Conclusion: There were gender differences in patients with OVCF,with a predilection for females and a wide age range of onset,with a peak after 60 years of age.Fractures are more likely to occur in the thoracolumbar segment and are mostly single-segment fractures.There is rapid pain relief in the early postoperative period and the height of the anterior border of the injured vertebra and the Cobb angle of the injured vertebra remain intact in the medium to long term(6 months postoperatively).There is still a risk of re-fracture after surgery and strict anti-osteoporosis treatment and health promotion are required. |
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