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A Comparative Study Of The Healing Effect Of A-PRF And CGF On Extraction Socket Of Mandibular Impacted Third Molars

Posted on:2023-02-22Degree:MasterType:Thesis
Country:ChinaCandidate:R DaiFull Text:PDF
GTID:2544307031458694Subject:Oral and clinical medicine
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Objective The aim of this study was to compare the clinical effect of healing effect of A-PRF and CGF on extraction socket after mandibular third molar extraction.Methods A total of 60 patients who voluntarily participated in this study after mandibular third molar extraction in Emergency General Hospital from October 2020 to November 2021 were divided into A-PRF group,CGF group and control group of 20 persons each.The extraction socket were filled with A-PRF membrane in A-PRF group and with CGF membrane in CGF group,and in the control group routine treatment was performed after the extraction.Clinical examination was conducted for the patients 1~7days after the operation to observe the wound healing and oral hygiene,as well as to compare the postoperative pain,swelling,bleeding at different time and the incidence of dry socket syndrome.CBCT measurement was performed three months after operation,and the changes of alveolar crest height and width,distal periodontal probing depth(PPD)and gingival recovery of adjacent second molars among the three groups were compared with those before operation.Results 1 The comparison on postoperative pain severity among the three groups showed that there was statistical significance on the 1st,2nd,3rd and 5th day after operation,the pain severity of A-PRF group and CGF group were better than the control group,but there was neither statistical significance between A-PRF group and CGF group,nor was that 7 days after operation(P>0.05).2 The comparison on the degrees of postoperative swelling among the three groups revealed that the experimental results were not statistically significant(P>0.05)on the 1st day after operation,but with significant differences at 2 days,3 days,5 days and 7 days after operation(P<0.05).On the 2nd,3rd and 5th day after operation,the results of A-PRF group and CGF group were better than control group,but there was no statistical significance between two experimental groups.According to the average value on the 7th day after operation,the CGF group was superior to the A-PRF group.3 The comparison on the postoperative bleeding among the three groups showed that at 30 minutes and day 1 after operation,there was statistical significance,the results of A-PRF group and CGF group were superior to the control group,while there was no statistical significance between A-PRF group and CGF group.The results were not statistically significant at 3 days,5 days and 7 days after operation(P>0.05).4 There was no significant difference in the incidence of dry socket among the three groups(P>0.05).5 The distance from bone alveolar crest to enamel cemental junction in the distal alveolar crests of adjacent second molars among the three groups was compared before and 3 months after operation,showing that there was no statistical significance in the data of buccoaxial angle,linguoaxial angle and alveolar crest before operation(P>0.05),but their differences were statistically significant at 3 months after operation(P<0.05).The comparison on average value of postoperative alveolar crests showed that the result in control group was superior to the other two groups,there was no statistical significance between CGF group and A-PRF group.6 There was no significant difference in the reduction of buccal-lingual alveolar bone width among the three groups before and 3 months after the operation(P>0.05).7 The comparisons on probing depths of buccal distal and lingual distal periodontium of mandibular second molars before and 3months after operation among the three groups showed that there was significant difference between the two parts before operation(P<0.05).8 The buccal distal and lingual distal gingival recovery in the three groups before and 3 months after operati on were compared,showing that there was significant difference in this respect(P<0.05).According to the average value,the result of the former in A-PRF group was better than that of the other two groups,the result of the latter in control group was inf erior to the other two groups,but that of A-PRF group was better than that CGF group.Conclusion The filling of A-PRF and CGF in the mandibular impacted third molar extraction socket can effectively relieve the postoperative pain,reduce the incidence of swelling and bleeding and contribute to the healing of the teeth extraction socket.Compared with natural healing,the distal bone defect and soft tissue loss of the second molar decreased significantly.The gingival recovery in A-PRF group was better than that of CGF group at 3 months after operation.Figure12;Table10;Reference165...
Keywords/Search Tags:mandibular wisdom tooth extraction, platelet concentrate(PC), advanced platelet rich fibrin(A-PRF), concentrate growth factor(CGF)
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