Association Between Haemoglobin Levels At Admission And Vascular Cognitive Impairment Cognitive Impairment After Ischemia Stroke

Objectives:We aimed to explore the relation between hemoglobin(HGB)levels at admission and vascular cognitive impairment(VCI)in patients after ischemic stroke.Methods:147 patients with ischemic stroke were included in this study from one hospital in Wuxi from December 2020 to July 2021.The first peripheral blood HGB after admission of all patients were collected.And then we divide them into anemia group and non-anemia group.The cognitive function was assessed within 14 days after stroke by mini-Mental State Examination(MMSE)、Montreal Cognitive Assessment(MoCA)and Ischemia Index Scale(HIS).Univariate and multivariate logistic regression models were used to analyze the relationship between ischemic VCI and HGB.Results:The incidence of VCI in anemia group was significantly higher than that in non-anemia group(P<0.05).Multivariate logistic regression analysis showed that,after adjusting for multiple covariables.HGB levels at admission was an independent factor for ischemic VCI in patients with ischemic stroke(P<0.05).Pearson correlation analysis showed that the HGB levels at admission was negatively correlated with the occurrence of VCI(r=-0.292.P<0.001).The lower the HGB levels,the higher the risk of VCI.Conslusions:Ischemic stroke patients with low HGB had a higher risk of VCI than those with normal HGB.It is suggested that early prevention and treatment of anemia may be beneficial to reduce the risk of VCI in patients with ischemic stroke.