Clinical Observation Of Toutou Mixture In Preventing Frequent Tension-type Headache Of Hyperactivity Of Liver-Yang

Objective:In this study,by observing the frequent tension headache(frequent tension type headache,FETTH)headache degree,headache days,headache duration,attacks,headache effect-6(headache impact test-6,HIT-6),traditional Chinese medicine syndrome efficacy score and headache index,objectively evaluate the clinical effect of headache,It provides a clinical basis for the treatment of headache mixture for frequent tension headache.Methods:This study adopted a clinical randomized controlled trial method and recruited a total of 96 subjects who met the trial criteria,including 32 in the traditional Chinese medicine group and 32 in the western medicine group,and 31 in the combination group.The traditional Chinese medicine group patients only took headache mixture,the western medicine group patients took amitriptyline hydrochloride tablets,and the combination group also took headache mixture and amitriptyline hydrochloride tablets.The treatment course for all three groups was 4 weeks,and the patient’s relevant scales were scored before and after treatment.The evaluation indicators are:degree of headache,duration of headache,number of attacks,HIT-6,traditional Chinese medicine syndrome efficacy score,and headache index efficacy score.Finally,statistical software was used to conduct statistical analysis on the collected data to objectively evaluate the clinical effect of headache mixture on frequent tension type headache with liver yang hyperactivity.result:1 Headache mixture is effective:All groups were clinically effective(P<0.05),The total effective rates of the combined group,the western medicine group and the traditional Chinese medicine group were 90.3%,68.7%and 71.9%respectively,and the difference in the total effective rates of each group was statistically significant(P<0.05).The total effective rate of the combined group was better than that of the traditional Chinese medicine group and the western medicine group.2 Traditional Chinese Medicine(TCM)syndrome and curative effect:TThe TCM syndromes of the three groups were improved,and the difference was statistically significant(P<0.05).The total effective rate of the combined group,the western medicine group and the traditional Chinese medicine group in terms of TCM syndrome was 90.3%,40.6%and 75%respectively.The combined group and the traditional Chinese medicine group were better than the western medicine group(P<0.05),and the combined group was better than the traditional Chinese medicine group(P<0.05).3 Headache mixture can reduce headache days:After treatment,the number of headache days in the three groups decreased significantly(P<0.05),while the number of attack days in the Chinese medicine group and the western medicine group was not statistically significant(P>0.05).The number of attack days after treatment in the combined group was less than that in the traditional Chinese medicine group,and the difference was statistically significant(P<0.05).The number of attack days after treatment in the combined group was less than that in the western medicine group(P<0.05),indicating that the curative effect of the traditional Chinese medicine group and the western medicine group was equivalent,and the combined group was superior to the western medicine group and the traditional Chinese medicine group.4 Number of headache attacks:After treatment,the number of headache attacks was reduced,and the difference was statistically significant(P<0.05).After treatment,the effect of the Chinese medicine group and the western medicine group was similar,without significant difference(P>0.05),and the combination group was significantly reduced compared with the Chinese medicine group and the western medicine group,and the difference was significant(P<0.05).5 Headache mixture can reduce headache duration:After treatment,the duration of headache in the three groups decreased significantly(P<0.05).After treatment,the Chinese medicine group and the western medicine group have the same effect in reducing the duration of headache,and the difference is not statistically significant(P>0.05).The combination group is significantly better than the Chinese medicine group and the western medicine group in reducing the duration of headache,and the difference is statistically significant(P<0.05),indicating that the three groups can reduce the number of headache attacks,and the combination group is better than the Chinese medicine group and the western medicine group.6 Headache mixture can reduce the severity of headache:After treatment,the vas score of patients in the three groups decreased significantly(P<0.05).After treatment,it was shown that the effect of headache mixture on reducing the severity of headache was the same as that of western medicine,with no statistically significant difference(P>0.05),but the effect of combination group on reducing the severity of headache was significantly higher than that of traditional Chinese medicine group and western medicine group,with a statistically significant difference(P<0.05).7 HIT-6:After treatment,the HIT-6 score of the three groups of patients decreased significantly(P<0.05).After treatment,the Chinese medicine group and the western medicine group had the same effect in improving the HIT-6 score,and the difference was not statistically significant(P>0.05).However,the combination group was significantly lower than the Chinese medicine group and the western medicine group in reducing the HIT-6 score,and the difference was statistically significant(P<0.05).8 Headache mixture improves and reduces headache index:The score of headache index in the three groups decreased significantly(P<0.05).There was no statistically significant difference in the headache index score between the traditional Chinese medicine group and the western medicine group(P=0.476>0.05).The headache index score of the combined group was lower than that of the traditional Chinese medicine group(P=0.040<0.001).The headache index score of the combined group was significantly lower than that of the western medicine group(P=0.004<0.05).Conclusion:1 Headache mixture has the same effect as the western medicine group in improving the degree of headache pain,the number of headache attacks,the number of headache attacks,the duration of headache,and the headache impact measurement-6 score,and the combination of traditional Chinese and western medicine has the better effect than the single drug.2 Headache mixture is better than amitriptyline hydrochloride in improving TCM syndromes,but the combination of the two is more effective.3 Headache mixture has no obvious adverse events and toxic side effects during the medication period,and is worthy of clinical promotion and application.