To Explore The Correlation Between Anxiety,Depression And TCM Constitution In Patients With Hepatitis B Cirrhosis By Bioelectrical Impedance Technique

Objective:The clinical data of 364 patients with hepatitis B cirrhosis with anxiety and depression were statistically analyzed.The factors affecting anxiety and depression in patients were analyzed.The correlation between anxiety and depression in patients with hepatitis B cirrhosis and TCM constitution was analyzed.The distribution of constitution was explored to provide evidence-based medical basis for the treatment of hepatitis B cirrhosis.Methods:According to the inclusion criteria and exclusion criteria of this study,the outpatients and inpatients in the Department of Hepatology of our hospital from January 2022 to December 2022 were screened.After obtaining the informed consent of the patients,the patients were instructed to fill in the self-rating anxiety scale,self-rating depression scale and TCM constitution classification and judgment table,and the body composition analyzer based on bioelectrical impedance technology was used to analyze the body composition,including total body water,protein,inorganic salt,body fat,skeletal muscle content and visceral fat area.The data obtained from the survey were recorded using Microsoft Excel tables and analyzed using statistical software SPSS 25.0 to analyze the relationship between TCM constitution,anxiety,depression and TCM constitution in patients with hepatitis B cirrhosis and the influencing factors of anxiety and depression.Results:1.Among the 364 patients with hepatitis B cirrhosis surveyed in this study,the distribution of TCM constitution is mainly biased constitution.According to the number of people,the top four are damp-heat constitution(28.85 %),phlegm-dampness constitution(23.07 %),qi-stagnation constitution(14.29 %),qi-deficiency constitution(13.46 %).2.Among the 364 patients with hepatitis B cirrhosis surveyed,193 had anxiety,with a prevalence of about 53.02 %,105 had depression,with a prevalence of about 28.85 %,and 105 had anxiety and depression,with a prevalence of about 28.85 %.3.The most common TCM constitutions of patients with hepatitis B cirrhosis complicated with anxiety and depression were damp-heat constitution,phlegm-dampness constitution and qi-stagnation constitution.There was statistical significance between mild constitution,phlegm-dampness constitution,qi-stagnation constitution and hepatitis B cirrhosis complicated with anxiety(P < 0.05),There was no significant difference between qi deficiency,yang deficiency,yin deficiency,damp heat,blood stasis and hepatitis B cirrhosis with anxiety(P > 0.05),Gentleness,qi stagnation and depression were statistically significant(P < 0.05),Qi deficiency,Yang deficiency,Yin deficiency,phlegm dampness,damp heat,blood stasis and hepatitis B cirrhosis with depression had no statistical significance(P > 0.05).4.Work intensity,education level,liver function Child-pugh classification and hepatitis B cirrhosis patients with anxiety and depression were statistically significant(P < 0.05),There was no significant difference in gender,age and anxiety and depression in patients with hepatitis B cirrhosis(P > 0.05).5.The total body water,protein,inorganic salt,body fat mass,skeletal muscle content and visceral fat area distribution of different TCM constitutions in patients with hepatitis B cirrhosis were different,but there was no statistical difference between the groups(P > 0.05).6.Protein,inorganic salt and hepatitis B cirrhosis patients with anxiety were statistically significant(P < 0.05),Protein,inorganic salt and visceral fat area were statistically significant with depression in patients with hepatitis B cirrhosis(P < 0.05).Conclusion:1.Among the 364 patients with hepatitis B cirrhosis in this study,there were 310 people with single TCM constitution and 54 people with combined constitution.The incidence of anxiety was about 53.02 %,and the incidence of depression was about 28.85 %.There was a correlation between gentleness,phlegm-dampness and qi stagnation and anxiety in patients with hepatitis B cirrhosis.There was a correlation between gentleness,qi stagnation and depression.The probability of anxiety and depression in patients with gentleness was low,and qi stagnation was a risk factor for anxiety and depression.2.Work intensity,education level and Child-pugh classification of liver function are related to anxiety and depression in patients with hepatitis B cirrhosis,which are risk factors for anxiety and depression.3.There was no correlation between TCM constitution distribution and body composition(total body water,protein,inorganic salt,body fat,skeletal muscle content,visceral fat area)in patients with hepatitis B cirrhosis.4.The occurrence of anxiety in patients with hepatitis B cirrhosis is related to protein and inorganic salt,and the occurrence of depression is related to protein,inorganic salt and visceral fat area.